Focus Your Search

Focus Your Search

(all filters optional)

Study TitleNCT NumberStatusConditionsInterventionsSponsorStudy Type
An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the CancerNCT02632409ACTIVE_NOT_RECRUITING
Various Advanced Cancer
  • Nivolumab
  • Placebo
Bristol-Myers SquibbINTERVENTIONAL
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic StrokeNCT05691244RECRUITING
Acute Ischemic Stroke
Cerebral Stroke
  • Drug: Normal Saline
  • Sovateltide
Pharmazz, Inc.INTERVENTIONAL
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on OsimertinibNCT04486833RECRUITING
Carcinoma, Non-Small Cell Lung
  • quaratusugene ozeplasmid
  • osimertinib
  • Platinum-Based Chemotherapy
Genprex, Inc.INTERVENTIONAL
N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial CancerNCT07217496NOT_YET_RECRUITING
Metastatic Urothelial Carcinoma
Urothelial Carcinoma
Locally Advanced Urothelial Carcinoma
Urothelial Cancer
  • Nogapendekin Alfa Inbakicept (N803)
  • Enfortumab Vedotin (EV)
  • Pembrolizumab
  • Research Biospecimen Collection
  • Radiographic Imaging
  • Tumor Biopsy
Vadim S KoshkinINTERVENTIONAL
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)NCT05254743RECRUITING
Chronic Lymphocytic Leukemia
Leukemia, Lymphocytic
Leukemia, B-cell
Small Lymphocytic Lymphoma
  • Pirtobrutinib
  • Ibrutinib
Loxo Oncology, Inc.INTERVENTIONAL
Study of AZD2811 + Durvalumab in ES-SCLCNCT04745689ACTIVE_NOT_RECRUITING
Small-Cell Lung Cancer
  • Durvalumab
  • AZD2811
  • Carboplatin
  • Cisplatin
  • Etoposide
AstraZenecaINTERVENTIONAL
A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic DermatitisNCT06311682RECRUITING
Atopic Dermatitis
  • Tralokinumab + TCS
  • Placebo + TCS
LEO PharmaINTERVENTIONAL
Nogapendekin Alfa Inbakicept for Advanced Non-Small Cell Lung CancerNCT03520686ACTIVE_NOT_RECRUITING
Non Small Cell Lung Cancer
  • NAI + Pembrolizumab
  • NAI + Nivolumab + Ipilimumab
  • Pembrolizumab
  • NAI + Pembrolizumab + Carboplatin + Nab-paclitaxel or Paclitaxel
  • Pembrolizumab + Carboplatin + Nab-paclitaxel or Paclitaxel (Investigator's choice)
  • Cisplatin/carboplatin and pemetrexed plus pembrolizumab.
  • Cisplatin/carboplatin and pemetrexed plus atezolizumab.
  • Carboplatin and paclitaxel plus atezolizumab and bevacizumab.
  • Carboplatin and nab-paclitaxel plus atezolizumab.
  • NAI + Nivolumab + Ipilimumab + Carboplatin + Nab-paclitaxel
ImmunityBio, Inc.INTERVENTIONAL
PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 MutationNCT05639751COMPLETED
Advanced Solid Tumor
Metastatic Solid Tumor
Non-small Cell Lung Cancers
SMARCA4 Gene Mutation
  • PRT3789
  • Docetaxel
Prelude TherapeuticsINTERVENTIONAL
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2NCT06952530RECRUITING
Hypertension
  • Orforglipron
  • Placebo
Eli Lilly and CompanyINTERVENTIONAL
RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia RadiosurgeryNCT02708810ACTIVE_NOT_RECRUITING
Trigeminal Neuralgia
  • Unframed Virtual Cone
  • 80 Gy Radiation
University of Alabama at BirminghamINTERVENTIONAL
A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)NCT06653153ACTIVE_NOT_RECRUITING
Alzheimer's Disease
  • Remternetug
  • Placebo
Eli Lilly and CompanyINTERVENTIONAL
Is Our Microbiome a Predictor of Cardiac RiskNCT02013284ENROLLING_BY_INVITATION
Coronary Artery Disease
N/AMayo ClinicOBSERVATIONAL
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid TumorsNCT06804824RECRUITING
Advanced Solid Tumors
  • VVD-159642
  • Sotorasib
  • Trametinib
Vividion Therapeutics, Inc.INTERVENTIONAL
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the HeartNCT06935370RECRUITING
Heart Failure
  • vicadrostat
  • empagliflozin
  • Placebo
Boehringer IngelheimINTERVENTIONAL
Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive IDH-1 Mutant GliomaNCT05484622RECRUITING
Astrocytoma
Oligodendroglioma
  • Vorasidenib
  • Pembrolizumab
Institut de Recherches Internationales ServierINTERVENTIONAL
Elbow Artery Embolization for Tennis ElbowNCT05325242RECRUITING
Lateral Epicondylitis, Unspecified Elbow
  • Embozene particles
Siddharth Padia, MDINTERVENTIONAL
Investigating the Impact of Obesity on Pubertal Development in GirlsNCT02583646RECRUITING
Obesity
Puberty
Normal Physiology
N/ANational Institute of Environmental Health Sciences (NIEHS)OBSERVATIONAL
Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple SclerosisNCT04480853RECRUITING
Multiple Sclerosis
  • Fingolimod
Novartis PharmaceuticalsINTERVENTIONAL
A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)NCT05296798RECRUITING
Locally Advanced or Metastatic Breast Cancer
  • Phesgo
  • Giredestrant
  • Docetaxel
  • Paclitaxel
  • LHRH Agonist
  • Optional Endocrine Therapy of Investigator's Choice
Hoffmann-La RocheINTERVENTIONAL
An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 TrialNCT06999798RECRUITING
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Locally Advanced Breast Carcinoma
  • Diagnostic Mammography
  • Resection
  • Ultrasound Imaging
  • Twinkling Marker Placement
Mayo ClinicINTERVENTIONAL
Cancer Within a Pandemic: A Telemental Health InterventionNCT04659993TERMINATED
Cancer
Survivorship
Depression, Anxiety
  • Telemental Health Sessions, Support Groups and Questionnaires
Wake Forest University Health SciencesINTERVENTIONAL
Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild AsthmaNCT06563102RECRUITING
Mild Asthma
  • Albuterol/Budesonide
  • Albuterol
AstraZenecaINTERVENTIONAL
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideNCT06897475RECRUITING
Type 2 Diabetes
  • LY3457263
  • Placebo
Eli Lilly and CompanyINTERVENTIONAL
QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder CancerNCT03022825ACTIVE_NOT_RECRUITING
Bladder Cancer
  • N-803 and BCG
  • N-803
ImmunityBio, Inc.INTERVENTIONAL
Integrative Medicine in Pain Management in Sickle Cell DiseaseNCT05045820ACTIVE_NOT_RECRUITING
Sickle Cell Disease
Pain
Acupuncture
Quantitative Sensory Testing
Magnetic Resonance Imaging
Circulating Biomarkers
Electroencephalography
Functional Near-infrared Spectroscopy
  • needling acupuncture
  • laser acupuncture
Indiana UniversityINTERVENTIONAL
An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus ErythematosusNCT05352919ENROLLING_BY_INVITATION
Systemic Lupus Erythematosus (SLE)
  • Litifilimab
  • Litifilimab-matching placebo
BiogenINTERVENTIONAL
A PHASED, PROSPECTIVE, MULTI-CENTER STUDY OF THE ELITA SYSTEMNCT05713253TERMINATED
Refractive Error
  • ELITA System
Johnson & Johnson Surgical Vision, Inc.INTERVENTIONAL
Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I MutationNCT06427811ACTIVE_NOT_RECRUITING
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
  • Asciminib
Novartis PharmaceuticalsINTERVENTIONAL
Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial HypercholesterolemiaNCT04652726COMPLETED
Familial Hypercholesterolemia - Heterozygous
  • Inclisiran
  • Placebo
Novartis PharmaceuticalsINTERVENTIONAL
Puberty, Sex Hormones and Pain Sensitivity in Adolescents With MigraineNCT05738213ACTIVE_NOT_RECRUITING
Migraine
  • Thermal stimuli
  • Pressure stimuli
  • Pain ratings
  • Pressure pain thresholds (PPT)
  • Conditioned pain modulation (CPM) response
  • PedMIDAS (Pediatric Migraine Disability Assessment)
  • Hormonal assessment
  • Pubertal status
Washington University School of MedicineINTERVENTIONAL
Expanded Access [11C] Methionine PET ImagingNCT05511714AVAILABLE
Central Nervous System Tumor
Head and Neck Neoplasms
  • L-(11C) methionine
St. Jude Children's Research HospitalEXPANDED_ACCESS
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine CancersNCT05882058RECRUITING
Small Cell Lung Carcinoma
Neuroendocrine Neoplasms
Extra-pulmonary Neuroendocrine Carcinoma
  • BI 764532, dose 1
  • BI 764532, dose 2
Boehringer IngelheimINTERVENTIONAL
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the KneeNCT07153471RECRUITING
Osteoarthritis
  • Orforglipron
  • Placebo
Eli Lilly and CompanyINTERVENTIONAL
E-mails to Nudge Safer and Better-Informed Prescribing of Risky DrugsNCT06443385ACTIVE_NOT_RECRUITING
Opioid Prescribing
Prescription Drug Misuse
  • PDMP Legal Mandate E-mail
  • PDMP Clinical Benefit E-mail
Columbia UniversityINTERVENTIONAL
S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAPNCT06188702RECRUITING
MTAP-deleted Solid Tumors
  • S095035
  • TNG462
Servier Bio-Innovation LLCINTERVENTIONAL
Left Bundle Branch Area Pacing (LBBAP) PMCF StudyNCT07217392RECRUITING
Bradycardia
Right Ventricular Pacing
Heart Failure
Atrial Fibrillation (AF)
Cardiac Disease
Left Bundle Branch Area Pacing
Conduction System Pacing
  • LBBAP lead
Abbott Medical DevicesINTERVENTIONAL
N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive GlioblastomaNCT06061809ACTIVE_NOT_RECRUITING
Glioblastoma
  • Bevacizumab
  • PD-L1 t-haNK
  • N-803
  • Tumor Treating Fields (TTFields, 200 kHz)
ImmunityBio, Inc.INTERVENTIONAL
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)NCT05716100RECRUITING
Focal Onset Seizures
  • XEN1101
  • Placebo
Xenon Pharmaceuticals Inc.INTERVENTIONAL
Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)NCT07149428NOT_YET_RECRUITING
Respiratory Tract Infection
Smell Disorder
Influenza
Rhinosinusitis
COVID-19
Depression
Parosmia
Hyposomia
Normosomia
Anosmia
N/ANational Institute on Deafness and Other Communication Disorders (NIDCD)OBSERVATIONAL
Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and SirolimusNCT04370795ENROLLING_BY_INVITATION
Severe Combined Immune Deficiency (SCID)
  • Sirolimus
  • Busulfan
  • Horse -Anti-thymocyte
  • G-CSF
  • Total Body Irradiation (TBI)
National Institute of Allergy and Infectious Diseases (NIAID)INTERVENTIONAL
Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)NCT07027839RECRUITING
Alcohol Use Disorder
  • Intravenous Ethanol
  • 18F-PF-06445974
National Institute of Mental Health (NIMH)INTERVENTIONAL
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)NCT07217717NOT_YET_RECRUITING
Pancreatic Ductal Adenocarcinoma (PDAC)
  • [18F]FAPI-74 PET/CT
SOFIEINTERVENTIONAL
A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related DiseaseNCT07190196RECRUITING
Immunoglobulin G4 Related Disease
  • Rilzabrutinib
  • Placebo
  • Glucocorticoid
SanofiINTERVENTIONAL
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell TransplantationNCT03856216TERMINATED
Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia
Lymphocytic Neoplasm
Lymphoma
  • Allogeneic Bone Marrow Transplantation
  • Bendamustine
  • Filgrastim-sndz
  • Fludarabine
  • Inotuzumab Ozogamicin
  • Melphalan
  • Peripheral Blood Stem Cell Transplantation
  • Rituximab
  • Tacrolimus
M.D. Anderson Cancer CenterINTERVENTIONAL
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C MutationNCT04449874ACTIVE_NOT_RECRUITING
Non-Small Cell Lung Cancer
Colorectal Cancer
Advanced Solid Tumors
  • GDC-6036
  • Atezolizumab
  • Cetuximab
  • Bevacizumab
  • Erlotinib
  • GDC-1971
  • Inavolisib
Genentech, Inc.INTERVENTIONAL
Clinical Trial of Ablation Therapy in Participants With Intermediate-Risk Non-Muscle Invasive Papillary Bladder CancerNCT06829823NOT_YET_RECRUITING
Non-muscle Invasive Bladder Cancer (NMIBC)
  • N-803 and BCG
  • N-803 and Gemcitabine
ImmunityBio, Inc.INTERVENTIONAL
Genetic Analysis of Uncommon Disease Presentations in Non-US PopulationsNCT06595940RECRUITING
Undiagnosed Diseases
Rare Diseases
N/ANational Human Genome Research Institute (NHGRI)OBSERVATIONAL
A Study of LY4175408 in Participants With Advanced CancerNCT07046923RECRUITING
Carcinoma, Non-Small-Cell Lung
Small Cell Lung Carcinoma
Endometrial Neoplasms
Neoplasm Metastasis
Triple Negative Breast Cancer
  • LY4175408
Eli Lilly and CompanyINTERVENTIONAL
L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AMLNCT06788756RECRUITING
Acute Myeloid Leukaemia (AML)
  • Placebo in combination with Cytarabine Injection
  • Liposomal Annamycin Injection in combination with Cytarabine Injection
  • Liposomal Annamycin Injection in combination with Cytarabine Injection
  • Liposomal Annamycin for Injection in combination with Cytarabine Injection.
Moleculin Biotech, Inc.INTERVENTIONAL
The GRoceries Aimed at Increasing Nutrition StudyNCT07167004RECRUITING
Type 2 Diabetes
Type II Diabetes Mellitus
Type II Diabetes
Pre-diabetes
Pre-diabetic
Pre-diabetic State
Type 2 Diabetes Mellitus (T2DM)
Type 2 Diabetes Mellitus
Type 2 Diabetes (T2DM)
  • Marketing Nudges Only
  • Marketing Nudges + Dynamically Adapted Financial Incentives
University of PennsylvaniaINTERVENTIONAL
Project: Every Child for Younger Patients With CancerNCT02402244RECRUITING
Adrenal Gland Pheochromocytoma
Carcinoma In Situ
Central Nervous System Neoplasm
Childhood Immature Teratoma
Childhood Kidney Neoplasm
Childhood Langerhans Cell Histiocytosis
Childhood Mature Teratoma
Congenital Mesoblastic Nephroma
Desmoid Fibromatosis
Ganglioneuroma
Lymphoproliferative Disorder
Malignant Neoplasm
Malignant Solid Neoplasm
Melanocytic Neoplasm
Myeloproliferative Neoplasm
Neoplasm of Uncertain Malignant Potential
Neuroendocrine Neoplasm
Stromal Neoplasm
  • Cytology Specimen Collection Procedure
  • Medical Chart Review
Children's Oncology GroupOBSERVATIONAL
Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated CytopeniasNCT05509582ENROLLING_BY_INVITATION
Immune Mediated Anemia
Immune Mediated Thrombocytopenia
Chronic GVHD
  • fostamatinib
National Heart, Lung, and Blood Institute (NHLBI)INTERVENTIONAL
Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or RisdiplamNCT05386680COMPLETED
Spinal Muscular Atrophy
  • OAV101
Novartis PharmaceuticalsINTERVENTIONAL
LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)NCT05321420ACTIVE_NOT_RECRUITING
Idiopathic Pulmonary Fibrosis
  • Placebo
  • Pirfenidone
  • Deupirfenidone
PureTechINTERVENTIONAL
A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic AtrophyNCT06769048RECRUITING
Geographic Atrophy
  • Placebo-matching BI 1584862
  • BI 1584862
Boehringer IngelheimINTERVENTIONAL
Optimization of Commissural Alignment During Transcatheter Aortic Valve Implantation With Evolut FX+NCT07217691NOT_YET_RECRUITING
Aortic Stenosis
Trans-catheter Aortic Valve Implantation
Commissural Alignment
  • Implantation of Evolut FX pluss TAVI device from Medtronic in LAO 25
  • Implantation of Evolut FX pluss TAVI device from Medtronic in patient specific degree.
Oslo University HospitalINTERVENTIONAL
Genetic Analyses of Nonsyndromic and Syndromic Deafness in PakistanNCT00341874ENROLLING_BY_INVITATION
Hearing Disorder
N/ANational Institute on Deafness and Other Communication Disorders (NIDCD)OBSERVATIONAL
ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid TumoursNCT06597721RECRUITING
Advanced Solid Tumor
  • ADCE-T02
Adcendo ApSINTERVENTIONAL
NHLBI-Emory Advanced Cardiac CT ReconstructionNCT05372627NOT_YET_RECRUITING
Structural Heart Disease
N/ANational Heart, Lung, and Blood Institute (NHLBI)OBSERVATIONAL
Assessment of a Fruit and Vegetable Prescription Program for ChildrenNCT04767282COMPLETED
Exposure to Fruit and Vegetable Prescription Program
  • Fruit and Vegetable Prescription
Michigan State UniversityINTERVENTIONAL
A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy AdultsNCT05703607RECRUITING
Shingles
Herpes Zoster Infection
Human
  • Candidate 1: PF-07915234: VZV modRNA Powder for Suspension for Injection
  • Candidate 1: PF-07915234: VZV modRNA Suspension for Injection
  • Candidate 2: PF-07921188: VZV modRNA Suspension for Injection
  • Candidate 3: PF-07921186: VZV modRNA Suspension for Injection
  • Shingrix
  • Candidate 2: PF-07921188: VZV modRNA Powder for Suspension for Injection
PfizerINTERVENTIONAL
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid TumorsNCT05954312RECRUITING
Advanced Solid Tumors
  • VVD-130037
  • Docetaxel
  • Paclitaxel
Vividion Therapeutics, Inc.INTERVENTIONAL
Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) TherapyNCT07186192RECRUITING
Hematologic Malignancies
  • Educational Intervention
  • Health Telemonitoring
  • Questionnaire Administration
  • Best Practice
City of Hope Medical CenterINTERVENTIONAL
A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)NCT06450639RECRUITING
Duchenne Muscular Dystrophy
  • Satralizumab
Hoffmann-La RocheINTERVENTIONAL
Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)NCT06041503NOT_YET_RECRUITING
Adenocarcinoma of the Bladder
Squamous Cell Carcinoma of the Bladder
Testicular Germ Cell Tumors
  • Pembrolizumab
  • Enfortumab vedotin
National Cancer Institute (NCI)INTERVENTIONAL
The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary StudyNCT04818034COMPLETED
Cystinuria
  • Dapagliflozin
University of California, San FranciscoINTERVENTIONAL
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia GravisNCT07217587NOT_YET_RECRUITING
Myasthenia Gravis
  • Nipocalimab
  • Efgartigimod
Janssen Research & Development, LLCINTERVENTIONAL
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid CancerNCT06991738NOT_YET_RECRUITING
Thyroid Cancer
  • 68Ga-DOTA-TATE PET Scan
  • Amino acid infusions
  • 177Lu-DOTA-EB-TATE
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)INTERVENTIONAL
STEMVAC in Patients With Early Stage Triple Negative Breast CancerNCT05455658ACTIVE_NOT_RECRUITING
Anatomic Stage IB Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage IIA Breast Cancer AJCC v8
Anatomic Stage IIB Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IIIA Breast Cancer AJCC v8
Anatomic Stage IIIB Breast Cancer AJCC v8
Anatomic Stage IIIC Breast Cancer AJCC v8
Prognostic Stage IB Breast Cancer AJCC v8
Prognostic Stage II Breast Cancer AJCC v8
Prognostic Stage IIA Breast Cancer AJCC v8
Prognostic Stage IIB Breast Cancer AJCC v8
Prognostic Stage III Breast Cancer AJCC v8
Prognostic Stage IIIA Breast Cancer AJCC v8
Prognostic Stage IIIB Breast Cancer AJCC v8
Prognostic Stage IIIC Breast Cancer AJCC v8
Triple-Negative Breast Carcinoma
  • CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine
  • Sargramostim
University of WashingtonINTERVENTIONAL
Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen SuppressionNCT03507608COMPLETED
Prostate Cancer
  • Flutamide
  • Placebo
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsINTERVENTIONAL
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)NCT06117774RECRUITING
Limited Stage Small Cell Lung Cancer
Small Cell Lung Cancer
  • Tarlatamab
  • Placebo
AmgenINTERVENTIONAL
Prospective Evaluation of Silk Fibroin Incision Dressings in ACL ReconstructionNCT07217613NOT_YET_RECRUITING
Anterior Cruciate Ligament Reconstruction
  • silk fibroin-based incision dressing
  • cyanoacrylate-based closure system
NYU Langone HealthINTERVENTIONAL
SMART-r: Substance Monitoring and Active Relapse Tracking RepositoryNCT06676059RECRUITING
Alcoholism
Substance-Related Disorders
N/ANational Institute on Drug Abuse (NIDA)OBSERVATIONAL
An Extension Study of Subcutaneous Secukinumab in Patients With Juvenile Psoriatic Arthritis (JPsA) and Enthesitis Related Arthritis (ERA)NCT03769168COMPLETED
Juvenile Psoriatic Arthritis
Enthesitis Related Arthritis
  • Secukinumab
Novartis PharmaceuticalsINTERVENTIONAL
A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer TreatmentNCT05889091RECRUITING
Head and Neck Squamous Cell Carcinoma
  • HRQOL instruments
  • LENT SOMA instrument
Memorial Sloan Kettering Cancer CenterINTERVENTIONAL
A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night SweatsNCT06049797ACTIVE_NOT_RECRUITING
Hot Flashes
  • Fezolinetant
  • Paroxetine
  • Citalopram
  • Escitalopram
  • Desvenlafaxine
  • Venlafaxine
  • Gabapentin
  • Clonidine
  • Pregabalin
  • Oxybutynin
  • Any other SSRI/SNRI not already specified
  • Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above
Astellas Pharma Global Development, Inc.OBSERVATIONAL
A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid ArthritisNCT06028438COMPLETED
Arthritis, Rheumatoid
  • Placebo
  • Nipocalimab
  • Certolizumab
Janssen Research & Development, LLCINTERVENTIONAL
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)NCT06077760RECRUITING
Non-small Cell Lung Cancer
  • Intismeran autogene
  • Pembrolizumab
  • Placebo
Merck Sharp & Dohme LLCINTERVENTIONAL
Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological InvolvementNCT06923072RECRUITING
Kohlmeier-Degos Disease
Malignant Atrophic Papulosis
Degos Disease
Papulosis, Malignant Atrophic
  • Baricitinib
National Heart, Lung, and Blood Institute (NHLBI)INTERVENTIONAL
Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell TransplantationNCT02669251ACTIVE_NOT_RECRUITING
Chronic Graft vs Host Disease
Chronic Graft-Versus-Host Disease
Bronchiolitis Obliterans Syndrome
  • MPH966
National Cancer Institute (NCI)INTERVENTIONAL
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)NCT07169630RECRUITING
Alzheimer s Disease
Mild Cognitive Impairment
Healthy
  • 18F-PF974
  • 18F-florbetaben
National Institute of Mental Health (NIMH)INTERVENTIONAL
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic MigraineNCT07018700RECRUITING
Episodic Migraine
  • Xeomin
  • Placebo
Merz Therapeutics GmbHINTERVENTIONAL
Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA StudyNCT04593277ACTIVE_NOT_RECRUITING
Clinical Stage I Cutaneous Melanoma AJCC v8
Clinical Stage II Cutaneous Melanoma AJCC v8
Clinical Stage III Cutaneous Melanoma AJCC v8
Hematopoietic and Lymphoid Cell Neoplasm
Invasive Malignant Neoplasm
Leukemia
Lymphoma
Malignant Solid Neoplasm
Sarcoma
Stage I Colorectal Cancer AJCC v8
Stage II Colorectal Cancer AJCC v8
Stage III Colorectal Cancer AJCC v8
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Thyroid Gland Carcinoma
  • Internet Mobile Technology
  • Internet-Based Intervention
  • Questionnaire Administration
  • Supportive Care
  • Informational Intervention
Fred Hutchinson Cancer CenterINTERVENTIONAL
A Study of Elranatamab (PF-06863135) in Chinese Participants With Refractory Multiple Myeloma.NCT05228470ACTIVE_NOT_RECRUITING
Elranatamab
Myeloma
Multiple Myeloma
Relapsed Multiple Myeloma
Refractory Multiple Myeloma
PF-06863135
BCMA
Bispecific
Bispecific Antibody
BCMA-CD3 Bispecific
MagnetisMM-8
  • Elranatamab
PfizerINTERVENTIONAL
A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult ParticipantsNCT05963984COMPLETED
Metastatic Breast Cancer
Locally Advanced Breast Cancer
Breast Cancer
  • Samuraciclib
  • Fulvestrant
Carrick Therapeutics LimitedINTERVENTIONAL
Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)NCT06596694RECRUITING
Gastrointestinal Cancer
  • Patritumab deruxtecan
Merck Sharp & Dohme LLCINTERVENTIONAL
Treating Pain in Children With Cancer: Pain BuddyNCT03384134COMPLETED
Cancer
  • Pain Buddy
University of California, IrvineINTERVENTIONAL
Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple MyelomaNCT06876142RECRUITING
Multiple Myeloma
Relapsed and/or Refractory Multiple Myeloma (RRMM)
  • Mirdametinib
  • Sirolimus
National Cancer Institute (NCI)INTERVENTIONAL
TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart FailureNCT03296813COMPLETED
Heart Failure
  • Torsemide
  • Furosemide
Duke UniversityINTERVENTIONAL
Fluid Status of ESRD Patients Undergoing DialysisNCT07217470RECRUITING
ESRD (End Stage Renal Disease)
N/AHemoCept Inc.OBSERVATIONAL
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 CirrhosisNCT06096779RECRUITING
Hepatocellular Carcinoma
  • Atezolizumab
  • Bevacizumab
Genentech, Inc.INTERVENTIONAL
SAGE LEAF 2: An Online Program to Reduce Dementia Caregiver BurdenNCT06708182RECRUITING
Caregiving Stress
Caregiver Burden
  • SAGE LEAF Positive Emotion Skills Course
Northwestern UniversityINTERVENTIONAL
A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal ImpairmentNCT07104162RECRUITING
Bacterial Infections
  • Cefiderocol/Xeruborbactam
Qpex Biopharma, Inc.INTERVENTIONAL
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCCNCT06788990RECRUITING
Metastatic Head and Neck Squamous Cell Carcinoma
Recurrent Head and Neck Squamous Cell Carcinoma
  • Ficerafusp alfa
  • Pembrolizumab (KEYTRUDA®)
  • Placebo
Bicara TherapeuticsINTERVENTIONAL
Mitigating the Disinhibiting Effects of Alcohol With Transcranial Magnetic StimulationNCT07188376NOT_YET_RECRUITING
Alcohol Risk Behaviors
  • Intermittent Theta Burst Stimulation
  • Continuous Theta Burst Stimulation
  • Sham Transcranial Magnetic Stimulation
Michael J. Wesley, PhDINTERVENTIONAL
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage MesotheliomaNCT06654050NOT_YET_RECRUITING
Mesothelioma
Malignant Mesothelioma (MM)
Early-stage Mesothelioma
Subclinical Mesothelioma
BRCA1-Associated Protein-1 (BAP1) Mutations
Early-stage BAP1-associated Malignancies
  • alrizomadlin
National Cancer Institute (NCI)INTERVENTIONAL
A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008)NCT03976362ACTIVE_NOT_RECRUITING
Carcinoma, Squamous Cell, Non-small-cell Lung
  • Pembrolizumab
  • Carboplatin
  • Paclitaxel
  • Nab-paclitaxel
  • Olaparib
  • Placebo
Merck Sharp & Dohme LLCINTERVENTIONAL
Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's DiseaseNCT04795466TERMINATED
Mild Cognitive Impairment
Alzheimer Disease
  • Canakinumab
  • Placebo
Novartis PharmaceuticalsINTERVENTIONAL
[Trial of device that is not approved or cleared by the U.S. FDA]NCT06903351WITHHELDN/AN/A[Redacted]N/A