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Study TitleNCT NumberStatusConditionsInterventionsSponsorStudy Type
A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityNCT06406465RECRUITING
Carcinoma, Neuroendocrine
Tumor, Neuroendocrine
Tumors, Neuroendocrine
Neuroendocrine; Carcinoma
Small Cell; Receptors
  • Belinostat
  • Cisplatin
  • Etoposide
National Cancer Institute (NCI)INTERVENTIONAL
Feasibility and Safety of a Portable Exoskeleton to Improve Mobility in Parkinson's DiseaseNCT06028529RECRUITING
Parkinson's Disease
  • Exoskeleton
VA Office of Research and DevelopmentINTERVENTIONAL
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)NCT06507748NOT_YET_RECRUITING
Neurofibromatosis Type 1
  • AlgometRx Nociometer
National Cancer Institute (NCI)INTERVENTIONAL
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive DisorderNCT03065335RECRUITING
Healthy Volunteer
Major Depressive Disorder
Depression
  • Ketamine
  • Placebo
  • Cobot TS MV robotic arm for TMS
  • NeurOptics PLRTM-30000 Pupillometer
National Institute of Mental Health (NIMH)INTERVENTIONAL
Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill PatientsNCT07173855NOT_YET_RECRUITING
Critical Illness
  • Magnesium sulfate administration
  • Magnesium oxide
  • Magnesium glucoheptonate
Scarborough General HospitalINTERVENTIONAL
Effect of Acupressure Applied Before Cystectomy on Preoperative Anxiety LevelNCT05325307COMPLETED
Anxiety
Hemodynamic Instability
  • Acupressure
  • Placebo acupressure
Mersin UniversityINTERVENTIONAL
Study of Families With Twins or Siblings Discordant for Rheumatic DisordersNCT00055055COMPLETED
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Idiopathic Inflammatory Myopathies
N/ANational Institute of Environmental Health Sciences (NIEHS)OBSERVATIONAL
Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)NCT06073821ACTIVE_NOT_RECRUITING
CLL
  • Sonrotoclax
  • Zanubrutinib
  • Venetoclax
  • Obinutuzumab
BeOne MedicinesINTERVENTIONAL
Xylitol Gum for Promoting Smoking CessationNCT07240545NOT_YET_RECRUITING
Smoking Cessation
Health Promotion
  • Brief smoking cessation advice
  • Warning leaflet
  • Self-help smoking cessation booklet
  • 4-week xylitol gum intervention
  • Instructional leaflet
  • 12-week instant message support
The University of Hong KongINTERVENTIONAL
Immunogenicity and Safety of Meningococcal Conjugate Vaccine (EG-MCV4) in Healthy Adults Aged 19 to 55 Years OldNCT07204457RECRUITING
Meningococcal Infections
  • EG-MCV4
  • Menveo
EyeGene Inc.INTERVENTIONAL
A Feasibility Study Implant of the WiSE® CRT System With an Intracardiac Pacemaker to Achieve Totally Leadless CRTNCT06561932NOT_YET_RECRUITING
Heart Failure
  • WiSE CRT System
EBR Systems, Inc.INTERVENTIONAL
A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell MalignanciesNCT06634589RECRUITING
B-cell Malignancy
Relapsed Cancer
Refractory Cancer
B-cell Lymphoma
  • BGB-16673
  • Sonrotoclax
  • Zanubrutinib
  • Mosunetuzumab
  • Glofitamab
  • Obinutuzumab
BeOne MedicinesINTERVENTIONAL
Effects of Protein Supplementation on 4 Weeks of Alternate-day Fasting on Fasting Blood Glucose, Resting Blood Pressure, and Body Composition in Young MenNCT07241689COMPLETED
Obesity & Overweight
  • protein supplement
  • No supplementation
Nanyang Technological UniversityINTERVENTIONAL
Influence of Methotrexate Discontinuation on Immunogenicity After PCV-20 Vaccine in Patients ARDsNCT07242092NOT_YET_RECRUITING
Autoimmune Rheumatic Diseases
  • Pneumococcal Vaccine
University of Sao Paulo General HospitalINTERVENTIONAL
EULAR Impact of Rheumatic and Musculoskeletal Diseases SurveyNCT06461000RECRUITING
Rheumatologic Disease
Musculoskeletal Diseases
  • Survey
European Alliance of Associations in RheumatologyOBSERVATIONAL
Comparison of Pharmacokinetics and Safety of HS632 and Xolair® With a Single InjectionNCT04361812TERMINATED
Similarity of Pharmacokinetics and Safety
  • HS632
  • Omalizumab (Xolair®)
BioRay Pharmaceutical Co., Ltd.INTERVENTIONAL
Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Plus Biceps Femoris Short Head Block in Patients Undergoing Knee Arthroscopy: A Prospective Randomized Controlled TrialNCT07242339NOT_YET_RECRUITING
Postoperative Pain Management
  • Adductor Canal Block (ACB) Only
  • biceps femoris short head block + Adductor Canal Block (ACB)
Kanuni Sultan Suleyman Training and Research HospitalINTERVENTIONAL
A Two-Part Phase 3 Study of LY4170156 in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian CancerNCT07213804RECRUITING
Ovarian Neoplasms
Fallopian Tube Neoplasms
Peritoneal Neoplasms
Neoplasm Metastasis
  • LY4170156
  • Paclitaxel
  • Topotecan
  • Gemcitabine
  • Pegylated liposomal doxorubicin
  • MIRV
  • Bevacizumab
  • Carboplatin
Eli Lilly and CompanyINTERVENTIONAL
MBC Physical Activity StudyNCT06500858COMPLETED
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Breast Carcinoma
  • Exercise Intervention
  • Exercise Intervention
  • Exercise Intervention
  • Health Promotion and Education
  • Internet-Based Intervention
  • Physical Activity
  • Questionnaire Administration
Thomas Jefferson UniversityINTERVENTIONAL
DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell CancersNCT04388852ACTIVE_NOT_RECRUITING
Aggressive Variant Prostate Carcinoma
Castration-Resistant Prostate Carcinoma
Metastatic Clear Cell Renal Cell Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Prostate Carcinoma
Metastatic Urothelial Carcinoma
Stage IV Prostate Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8
  • Ipilimumab
  • Valemetostat
M.D. Anderson Cancer CenterINTERVENTIONAL
Clamp Study to Estimate the Relative Potency of GZR33 Versus Insulin Degludec at Steady StateNCT07242664RECRUITING
Type 1 Diabetes Mellitis
  • GZR-33
Gan and Lee Pharmaceuticals, USAINTERVENTIONAL
A Phase I/II Clinical Trial on the Per-operative Intratumoral Administration of Myeloid Dendritic Cells Plus Ipilimumab and Nivolumab, Followed by Repeated Intracavitary Plus Intravenous Administration of Nivolumab in Patients With Recurrent Glioblastoma.NCT03233152ACTIVE_NOT_RECRUITING
Glioblastoma
  • Ipilimumab (YervoyTM, 50 mg/10 mL solution)
  • Nivolumab (OpdivoTM, 40 mg/4mL solution)
  • Autologous CD1c(BDCA-1)+ /CD141(BDCA-3)+ myDC
Universitair Ziekenhuis BrusselINTERVENTIONAL
Defining TRPV4 Contribution of Schwann Cells to Oral Cancer PainNCT07095608RECRUITING
Oral Cancer
Squamous Cell Carcinoma
  • Pressure and stretch sensitivity testing
New York UniversityINTERVENTIONAL
Comparing the Safety and Efficacy of First-line Polychemotherapy and Polychemotherapy in Combination With PIPAC SessionsNCT06313801RECRUITING
Gastric Cancer
  • Docetaxel
  • Oxaliplatin
  • Calcium folinate
  • Fluorouracil
  • Diagnostic laparoscopy
  • dPIPAC ( The description of the standard diagnostic laparoscopy procedure and the session of PIPAC (dPIPAC)).
Nizhny Novgorod Regional Clinical Oncology CenterINTERVENTIONAL
Transfusion of Pathogen Reduced Cryoprecipitated Fibrinogen to Expedite Product Availability in Perioperative BleedingNCT05711524COMPLETED
Hypofibrinogenemia
Bleeding
  • Traditional Cryoprecipitate
  • Pathogen-Reduced Cryoprecipitate
Weill Medical College of Cornell UniversityINTERVENTIONAL
Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)NCT06280820ENROLLING_BY_INVITATION
Heart Failure
N/ANational Heart, Lung, and Blood Institute (NHLBI)OBSERVATIONAL
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple MyelomaNCT04973605RECRUITING
Relapsed/Refractory Multiple Myeloma
  • Sonrotoclax
  • Dexamethasone
  • Carfilzomib
  • Daratumumab
  • Pomalidomide
BeOne MedicinesINTERVENTIONAL
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: BevacizumabNCT06701656RECRUITING
Acute Respiratory Distress Syndrome (ARDS)
ARDS
ARDS (Acute Respiratory Distress Syndrome)
Acute Respiratory Distress Syndrome
  • Cohort C: bevacizumab
  • Cohort C: placebo
PPD Development, LPINTERVENTIONAL
Urinary Incontinence in Older Hong Kong Women: A Cross-sectional StudyNCT07243223NOT_YET_RECRUITING
Urinary Incontinence in Old Age
N/AHong Kong Baptist UniversityOBSERVATIONAL
DEBSCAN-IVL. Drug Eluting Balloon or Drug Eluting Stent to Treat CAlcified Nodules After IntraVascular Lithotripsy.NCT06657833RECRUITING
Coronary Artery Disease
  • Percutaneous coronary intervention of a calcified nodule with intravascular lithotripsy followed by drug eluting balloon
  • Percutaneous coronary intervention of a calcified nodule with intravascular lithotripsy followed by drug eluting stent
Fundación EPICINTERVENTIONAL
Electroacupuncture for Opioid-Induced Constipation in Cancer Patients: A Randomized Clinical TrialNCT06537440COMPLETED
Constipation, Opioid-Induced
Cancer
  • Electroacupuncture
First Teaching Hospital of Tianjin University of Traditional Chinese MedicineINTERVENTIONAL
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenNCT00862433COMPLETED
Diabetes
Fatty Liver
Obesity
Healthy Volunteers
  • Alpha tocopherol
  • Vitamin E
  • Vitamin C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)INTERVENTIONAL
Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)NCT07241585NOT_YET_RECRUITING
Nonmelanoma Skin Cancer
Basal Cell Carcinoma
Squamous Cell Carcinoma
  • Vitamin D (VitD)
  • Placebo
  • Photodynamic therapy (PDT)
  • Mohs surgery or electrodessication & curettage (ED&C) (standard of care)
Case Comprehensive Cancer CenterINTERVENTIONAL
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CPNCT04971226ACTIVE_NOT_RECRUITING
Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive
  • Imatinib
  • Nilotinib
  • Bosutinib
  • Dasatinib
  • Asciminib
Novartis PharmaceuticalsINTERVENTIONAL
Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell TransplantNCT06856226RECRUITING
Leukemia
Lymphoma
Hematologic Malignancy
  • Arm 1
National Cancer Institute (NCI)OBSERVATIONAL
Botulinum Toxin for the Treatment of Involuntary Movement DisordersNCT00001208RECRUITING
Movement Disorders
N/ANational Institute of Neurological Disorders and Stroke (NINDS)OBSERVATIONAL
A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal ImpairmentNCT07165015RECRUITING
Renal Impairment
Healthy
Renal Insufficiency
End Stage Renal Disease (ESRD)
  • LY3537031
Eli Lilly and CompanyINTERVENTIONAL
A Pilot Study on Efficacy of Digital Therapeutic NDTx-02 for Executive Function in Children and Adolescents With ADHD or ASDNCT07242625RECRUITING
Attention-Deficit/Hyperactivity Disorder
Autism Spectrum Disorder
  • NDTx-02 + TAU
  • TAU
Neudive Inc.INTERVENTIONAL
Efficacy of INM004 in Children With STEC-HUSNCT06389474RECRUITING
Hemolytic-Uremic Syndrome
  • INM004
  • Placebo
Inmunova S.A.INTERVENTIONAL
Reducing Heart Failure Risk in Late-Life With Physical ActivityNCT06247774NOT_YET_RECRUITING
Hypertension
Exercise Training
Cardiac Rehabilitation
Proteomics
  • Cardiac Rehabilitation
  • Attention Control
Brigham and Women's HospitalINTERVENTIONAL
The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients.NCT06377605COMPLETED
Erector Spinae Plane Block
Super Obese Patients
Bariatric Surgery
  • ESPB
  • local anaesthetic infiltration
  • midazolam and lidocaine
  • Bupivacain
Amany Ahmed EissaINTERVENTIONAL
Evaluation of Vitamin A Absorption From Fortified BouillonNCT06438562ACTIVE_NOT_RECRUITING
Healthy Volunteers
Vitamin A
  • Unfortified bouillon plus vitamin A in oil
  • Bouillon fortified with vitamin A #1 plus unfortified oil
  • Bouillon fortified with vitamin A #2 plus unfortified oil
University of Wisconsin, MadisonINTERVENTIONAL
Transition to Adulthood Through Coaching and EmpowermentNCT05570617ACTIVE_NOT_RECRUITING
Juvenile Idiopathic Arthritis
Inflammatory Bowel Diseases
  • Transition Coach Intervention
  • Standard of Care- Youth Transition Roadmap
McMaster UniversityINTERVENTIONAL
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's DiseaseNCT07170150RECRUITING
Alzheimers Disease
  • Trontinemab
  • Placebo
Hoffmann-La RocheINTERVENTIONAL
Outcomes of Placenta Accreta Spectrum Disorders Surgery in Relation to Placenta Accreta Scoring IndexNCT06220760COMPLETED
Placenta Previa
Placenta Accreta
  • Ultrasound
Assiut UniversityOBSERVATIONAL
REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active MenNCT04838769ACTIVE_NOT_RECRUITING
Benign Prostatic Hyperplasia (BPH)
  • REZŪM
  • alpha blocker and 5-alpha reductase inhibitor
Boston Scientific CorporationINTERVENTIONAL
Medico-economic Comparison of Robot-assisted Radical Prostatectomy Versus Radical Prostatectomy Via LaparotomyNCT01577836COMPLETED
Prostatic Neoplasms
N/ACentre Hospitalier Universitaire de NīmesOBSERVATIONAL
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)NCT06667700RECRUITING
Coronavirus Disease (COVID-19)
  • Molnupiravir
  • Placebo
Merck Sharp & Dohme LLCINTERVENTIONAL
This Clinical Investigation Assesses the Safety and Performance of a New Beamformer for MED-EL Cochlear Implant Recipients.NCT07213505RECRUITING
Cochlear Implant Users
  • Testing new front-end features
MED-EL Elektromedizinische Geräte GesmbHINTERVENTIONAL
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular DegenerationNCT06660667RECRUITING
Neovascular Age-related Macular Degeneration
  • SAR402663
  • Diluent
SanofiINTERVENTIONAL
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria ChallengeNCT02639299RECRUITING
Malaria
N/ANational Institute of Allergy and Infectious Diseases (NIAID)OBSERVATIONAL
Brain Gym Exercises on Risk of Fall, Balance and Quality of Life in Obese SubjectsNCT06587932COMPLETED
Obese Subjects
  • brain gym exercises
  • Traditional treatments
Cairo UniversityINTERVENTIONAL
Role of Cervical Fascia Flap in Decreasing the Incidence of Pharyngocutaneous Fistula After Total LaryngectomyNCT07241611COMPLETED
Malignant Tumor of the Larynx
  • Total laryngectomy
Mansoura UniversityINTERVENTIONAL
Genetic Markers for Focal Segmental GlomerulosclerosisNCT00001393COMPLETED
Focal Segmental Glomerulosclerosis
HIV-Associated Focal Segmental Glomerulosclerosis
N/ANational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)OBSERVATIONAL
Developing the Family Map: Looking at Communal CopingNCT01633021COMPLETED
Sickle Cell
Diabetes
Cancer
Cardiovascular Disease
Genetic Screening
N/ANational Human Genome Research Institute (NHGRI)OBSERVATIONAL
Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot UlcersNCT07161830NOT_YET_RECRUITING
Diabetic Foot Ulcer
  • Omeza® Complete Matrix
  • Standard of Care
Omeza, LLCINTERVENTIONAL
Therapy Adapted for High Risk and Low Risk HIV-Associated Anal CancerNCT04929028RECRUITING
AIDS-Related Anal Carcinoma
Anal Margin Squamous Cell Carcinoma
Anal Non-Keratinizing Squamous Cell Carcinoma
Anal Squamous Cell Carcinoma
HIV Infection
Rectal Squamous Cell Carcinoma
Stage II Rectal Cancer AJCC v8
Stage IIB Anal Cancer AJCC v8
Stage III Anal Cancer AJCC v8
Stage III Rectal Cancer AJCC v8
  • Anoscopy
  • Biospecimen Collection
  • Capecitabine
  • Colonoscopy
  • Computed Tomography
  • Digital Rectal Examination
  • Echocardiography Test
  • Fludeoxyglucose F-18
  • Fluorouracil
  • Intensity-Modulated Radiation Therapy
  • Lymph Node Biopsy
  • Magnetic Resonance Imaging
  • Mitomycin
  • Nivolumab
  • Positron Emission Tomography
  • Proctoscopy
  • Questionnaire Administration
  • Sigmoidoscopy
National Cancer Institute (NCI)INTERVENTIONAL
Predicting Future Errors During Skill PerformanceNCT06707207RECRUITING
Healthy
N/ANational Institute of Neurological Disorders and Stroke (NINDS)OBSERVATIONAL
Modified HFNC Therapy for ARF Patients Undergoing Flexible BronchoscopyNCT05759832COMPLETED
Acute Hypoxemic Respiratory Failure
High-flow Nasal Cannula Oxygen
  • Modified HFNC oxygen therapy
  • Non-rebreathing reservoir mask
Beijing Chao Yang HospitalINTERVENTIONAL
A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)NCT06405087RECRUITING
Ulcerative Colitis
Crohn's Disease
  • Vedolizumab SC
  • No Intervention
TakedaINTERVENTIONAL
Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total ThyroidectomyNCT02924532COMPLETED
Hypoparathyroidism
  • immediate post operative bioassay of Parathyroid Hormone
Centre Hospitalier Universitaire de NīmesOBSERVATIONAL
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With CancerNCT02108028COMPLETED
HIV
Cancer
Chronic Granulomatous Disease
Dock 8 Deficiency
N/ANational Cancer Institute (NCI)OBSERVATIONAL
Lagged Relationships Between Sleep, Balance, and Cognition in Older AdultsNCT06584136COMPLETED
Aging
N/AUniversity of FloridaOBSERVATIONAL
Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative NeoplasmsNCT06303193NOT_YET_RECRUITING
Myelodysplastic Syndromes
  • pacritinib
National Cancer Institute (NCI)INTERVENTIONAL
Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue HypoperfusionNCT04166331COMPLETED
Sepsis
Cardiomyopathies
Hypoperfusion
Left Ventricular Systolic Dysfunction
  • Placebos
  • Dobutamine
University Hospital, LimogesINTERVENTIONAL
Comparative Effectiveness Trial for Diagnosis of Necrotizing EnterocolitisNCT05573113COMPLETED
Necrotizing Enterocolitis
  • Bowel Ultrasound
  • Abdominal radiograph
Children's Mercy Hospital Kansas CityINTERVENTIONAL
A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.NCT04116541RECRUITING
Malignant Solid Tumor
  • HDM201
  • Ribociclib
  • Cabozantinib
  • Alectinib
  • Regorafenib
  • Trametinib
  • Dabrafenib
  • Avapritinib
Centre Leon BerardINTERVENTIONAL
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell LymphomaNCT03223610RECRUITING
Lymphoma
Non-Hodgkin Lymphoma
Diffuse Large B-Cell Lymphoma
Burkitt Lymphoma
  • Venetoclax
  • Ibrutinib
  • Prednisone
  • Obinutuzumab
  • Revlimid (lenalidomide)
National Cancer Institute (NCI)INTERVENTIONAL
Impact of Budesonide on Incidence of ≥ Gr2 Diarrhea in Multiple Myeloma (MM) Patients Undergoing Autologous Stem Cell TransplantNCT05405387RECRUITING
Multiple Myeloma
  • Budesonide EC
  • Placebo
University of UtahINTERVENTIONAL
BabySTrong II taVNS Feeding TrialNCT07049952RECRUITING
Feeding Delays
Neonates and Term Infants
  • taVNS
  • NAC and taVNS
  • inactive taVNS
  • sterile water and inactive taVNS
Medical University of South CarolinaINTERVENTIONAL
A Study to Assess the Relative Bioavailability After a Single Inhalation Administration of Treprostinil Palmitil Inhalation Powder (TPIP) Formulation 2 (F2) to TPIP Formulation 3 (F3) in Healthy ParticipantsNCT07102316COMPLETED
Healthy Volunteers
  • TPIP F2
  • TPIP F3
Insmed IncorporatedINTERVENTIONAL
Non-Invasive Respiratory MonitorNCT02851043RECRUITING
Neuromuscular Diseases
Healthy Volunteers
  • pneuRIP (breathing with resistance)
  • Respitrace system (Carefusion) (breathing without resistance)
Nemours Children's ClinicINTERVENTIONAL
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With ObesityNCT05713799NOT_YET_RECRUITING
Insulin Resistance
Obesity
  • Placebo
  • Mirabegron
  • Alpha-lipoic acid
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)INTERVENTIONAL
Ultrasound for the Detection of Oxaliplatin-Induced Peripheral NeuropathyNCT03958747COMPLETED
Gastrointestinal Cancer
Colorectal Cancer
  • Ultrasound - Serial and Tibial Nerve
  • Skin Biopsy
  • Abbreviated Neurologic Exam
  • Blood draw
  • Nerve Conduction Study
  • QLQ-CIPN20 Questionnaire Administration
Wake Forest University Health SciencesINTERVENTIONAL
Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization. A Randomized Controlled TrialNCT07242534NOT_YET_RECRUITING
Infertility
Obesity
  • Semaglutide
  • No pre-treatment
Fundacion DexeusINTERVENTIONAL
Core Stabilization Training in Child and Adolescent Underwater Rugby AthletesNCT06728267COMPLETED
Core Stabilization
Trunk Muscle Endurance
Respiratory Function
Quality of Life
  • Core stabilization training
  • Training
Ozden GokcekINTERVENTIONAL
Safety, Tolerability and PK of ATTO-3712 in Healthy Volunteers and Patients With Atopic DermatitisNCT07205081RECRUITING
Normal Volunteers
Atopic Dermatitis (AD)
Atopic Eczema
Atopic Eczema/Dermatitis (Non-Specific)
  • ATTO-3712
  • Placebo
Attovia Therapeutics IncINTERVENTIONAL
Relationship Between Muscle Oxygenation and Upper Extremity Exercise Capacity in Patients With Chronic Neck PainNCT07241312NOT_YET_RECRUITING
Chronic Neck Pain
N/AKirsehir Ahi Evran UniversitesiOBSERVATIONAL
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.NCT06072612RECRUITING
Breast Cancer
Metastatic Breast Cancer
Breast Neoplasm
Breast Cancer Metastatic
End Stage Cancer
  • SV-BR-1-GM
  • Cyclophosphamide
  • Interferon infiltration of the inoculation site
  • Retifanlimab
  • Treatment of Physician's Choice
BriaCell Therapeutics CorporationINTERVENTIONAL
Natural History of Craniofacial Anomalies and Developmental Growth VariantsNCT02639312RECRUITING
Prognathism
Retrognathism
Dentofacial Deformities
N/ANational Institute of Dental and Craniofacial Research (NIDCR)OBSERVATIONAL
A Community-based Prospective Cohort Study on Metabolic Dysfunction-Associated Fatty Liver Disease in Older Adults: From Metabolic Trajectories to Extrahepatic OutcomesNCT07241195NOT_YET_RECRUITING
NAFLD and NASH
NAFLD( Non-alcoholic Fatty Liver Disease )
NAFLD Cirrhosis
N/AThe Affiliated Hospital of Hangzhou Normal UniversityOBSERVATIONAL
Impact of Clinical Pharmacist on the Quality and Cost of the Therapeutic Management of Patients in Two Medical Services of a Teaching HospitalNCT02887001COMPLETED
Admitted to Infectiology or Internal Medicine Wards
  • Pharmacist consultation
Centre Hospitalier Universitaire de NīmesINTERVENTIONAL
Brain Stimulation and Vision TestingNCT01617408RECRUITING
fMRI
Dorsal Pathway
Ventral Pathway
N/ANational Institute of Mental Health (NIMH)OBSERVATIONAL
ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot StudyNCT00410241ACTIVE_NOT_RECRUITING
Healthy Volunteers
Atherosclerotic Heart Disease
N/ANational Human Genome Research Institute (NHGRI)OBSERVATIONAL
Multicentric RCT Comparing High Purity Type I Collagen-Skin Substitute vs dHACM in Treatment of Diabetic Foot UlcersNCT07046403COMPLETED
Diabetic Foot Ulcer (DFU)
  • High Purity Type-I Collagen-based Skin Substitute and SOC
  • Dehydrated Human Amnion / Chorion Membrane and SOC
Adichunchanagiri Institute of Medical Sciences, B G NagaraINTERVENTIONAL
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)NCT01419561RECRUITING
KSHV Inflammatory Cytokine Syndrome (KICS)
KSHV
HHV-8
  • Zidovudine
  • Liposomal Doxorubicin
  • Valganiclovir
  • Rituximab
  • Standard Therapies
  • Cohort 1
National Cancer Institute (NCI)INTERVENTIONAL
Association Between Lingual Retraction and Hemodynamic Changes in Patients Receiving Dental Treatment Under General AnesthesiaNCT07240688RECRUITING
Trigeminocardiac Reflex
Hemodynamic Changes
Dental Procedures
N/AKırıkkale UniversityOBSERVATIONAL
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid TumorsNCT07006727RECRUITING
Small Cell Lung Carcinoma
Large Cell Neuroendocrine Carcinoma of the Lung
Neuroendocrine Prostate Cancer
Gastroenteropancreatic Neuroendocrine Carcinoma
  • 225Ac-ETN029
  • 111In-ETN029
Novartis PharmaceuticalsINTERVENTIONAL
A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital HerpesNCT06385327ACTIVE_NOT_RECRUITING
Recurrent Genital Herpes Simplex Type 2
  • ABI-5366
  • ABI-5366 Placebo
Assembly BiosciencesINTERVENTIONAL
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia: a Randomized Controlled Trial.NCT07242573RECRUITING
Fibromyalgia
Chronic Fatigue Syndrome (CFS)
  • Physical Training Program
  • NESA X-Signal
  • Conventional Physiotherapy
National Institute of Geriatrics, Rheumatology and Rehabilitation, PolandINTERVENTIONAL
Using Plasma Human Papillomavirus (HPV)-Related Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) to Follow Response of Cervical Cancer to Surgery, Radiation, and ChemotherapyNCT07214584NOT_YET_RECRUITING
Cervical Cancer
Human Papilloma Virus (HPV)
N/AUniversity of FloridaOBSERVATIONAL
Taste Alterations StudyNCT06669416RECRUITING
Chemotherapy Side Effects
Taste, Altered
  • Taste Alteration Self-Assessment
  • Taste Alternation Self-Management
Wake Forest University Health SciencesINTERVENTIONAL
Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous SystemNCT00794352RECRUITING
Central Nervous System Disease
Multiple Sclerosis
N/ANational Institute of Allergy and Infectious Diseases (NIAID)OBSERVATIONAL
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)NCT07165028RECRUITING
Metabolic Dysfunction-Associated Steatotic Liver Disease
  • Tirzepatide
  • Retatrutide
  • Placebo
Eli Lilly and CompanyINTERVENTIONAL
Allogeneic Hematopoietic Stem Cell Transplant for GATA2 MutationsNCT01861106RECRUITING
GATA2
Immunodeficiency
MDS
  • Allogeneic HSCT
  • Busulfan Test dose
  • Fludarabine (Fludara, Berlex Laboratories)
  • Busulfan (Busulfex)
  • Cyclophosphamide (CTX, Cytoxan)
  • Total Body Irradiation (TBI)
  • Mycophenolate mofetil (MMF)
  • Tacrolimus
  • Equine Anti-Thymocyte Globulin
National Cancer Institute (NCI)INTERVENTIONAL
Expanded Access Program for Treatment With Ecopipam for Tourette's DisorderNCT07093541TEMPORARILY_NOT_AVAILABLE
Tourettes Disorder
Tourette Disorder
  • ecopipam HCl ~2mg/kg/day
Emalex Biosciences Inc.EXPANDED_ACCESS
A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)NCT06345729RECRUITING
Non-small Cell Lung Cancer
  • MK-1084
  • Placebo
  • Pembrolizumab
Merck Sharp & Dohme LLCINTERVENTIONAL
Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell DeathNCT00246857RECRUITING
Primary Immune Deficiency
N/ANational Institute of Allergy and Infectious Diseases (NIAID)OBSERVATIONAL
A Study in Healthy Adults to Compare the Bioavailability of EPA + DHA From Two Microalgal Sources to One Fish Source and PlaceboNCT07241377RECRUITING
Absorption of Omega-3
Omega-3 Supplementation
Healthy Participants
  • life'sTM omega O1035DS nTG
  • life'sTM omega O3020DS nTG
  • MEG-3 3323rTG
  • Placebo
RDC Clinical Pty LtdINTERVENTIONAL
Family Study of Affective and Anxiety Spectrum DisordersNCT00071786COMPLETED
Mood Disorders
Sleep Disorders
Migraine
N/ANational Institute of Mental Health (NIMH)OBSERVATIONAL