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Study TitleNCT NumberStatusConditionsInterventionsSponsorStudy Type
Emotional Awareness and Expression Therapy (EAET) as a Novel Migraine TreatmentNCT05837650COMPLETED
Migraine Disorders
  • Emotional Awareness and Expression Therapy (EAET)
University of UtahINTERVENTIONAL
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's DiseaseNCT07048197RECRUITING
Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
  • Rapcabtagene autoleucel
Novartis PharmaceuticalsINTERVENTIONAL
Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid TumorsNCT07151040RECRUITING
Solid Tumor
Colorectal Cancer (CRC)
Squamous Cell Carcinoma of Head and Neck
Non-Small Cell Lung Cancer (NSCLC)
Gastrooesophageal Junction Cancer
Gastric Cancer
  • TH9619
One-carbon Therapeutics ABINTERVENTIONAL
Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related ConditionsNCT03510442RECRUITING
Still's Disease, Adult-Onset
Systemic Inflammation
Arthritis
Autoinflammatory Syndrome
N/ANational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)OBSERVATIONAL
Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell DiseaseNCT07252050NOT_YET_RECRUITING
Sickle Cell Disease
Hematopoetic Stem Cell Transplant
Haploidentical Hematopoietic Stem Cell Transplant
Haploidentical Stem Cell Transplantation
Graft Failure
  • Ruxolitinib
University of Colorado, DenverINTERVENTIONAL
A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet SyndromeNCT06872125RECRUITING
Dravet Syndrome
  • zorevunersen
  • Sham Comparator
Stoke Therapeutics, IncINTERVENTIONAL
Psilocybin to Treat Depression in Spinal Cord InjuryNCT07251491NOT_YET_RECRUITING
Spinal Cord Injury
Depression - Major Depressive Disorder
Veteran
  • Psilocybin (Usona Institute)
James J. Peters Veterans Affairs Medical CenterINTERVENTIONAL
Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 DiabetesNCT06706284RECRUITING
Spinal Cord Injuries
Type 2 Diabetes
  • Semaglutide Injectable Product
  • Placebo
Marzieh SalehiINTERVENTIONAL
Phase II Study Evaluating the Efficacy and Safety of the Combination of Tagraxofusp and Venetoclax in Treatment-naive Blastic Plasmacytoid Dendritic Cell Neoplasm PatientsNCT07007052NOT_YET_RECRUITING
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
  • Venetoclax
  • Tagraxofusp
French Innovative Leukemia OrganisationINTERVENTIONAL
MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled TrialNCT03892785ACTIVE_NOT_RECRUITING
Giant Cell Arteritis
  • Prednisone treatment
  • Tocilizumab treatment
  • Methotrexate treatment
  • Questionnaires
  • Blood samples
Centre Hospitalier Universitaire DijonINTERVENTIONAL
Questionnaire and Tissue Banking For Multiple Myeloma, Waldenstrom Macroglobulinemia and Related DisordersNCT01177527ACTIVE_NOT_RECRUITING
Multiple Myeloma
Waldenstrom's Macroglobulinemia
Smoldering Multiple Myeloma
Lymphoblastic Lymphoma
N/ADana-Farber Cancer InstituteOBSERVATIONAL
LCMS-Based Metabolic Analysis Explores the Effect of American Ginseng on Urine and Plasma in Healthy IndividualsNCT07252362RECRUITING
The Impact of American Ginseng on the Metabolomics of Urine and Plasma in Healthy Individuals
  • American Gginseng
Zhejiang Cancer HospitalINTERVENTIONAL
Investigation of Impact of AI on Prostate Cancer WorkflowNCT07084779RECRUITING
Prostate Cancer
Prostatic Neoplasm
Cancer of the Prostate
Neoplasms, Prostate
  • AI
Case Comprehensive Cancer CenterINTERVENTIONAL
Positive Psychology Intervention for Patients Post-bariatric Surgery and Their PartnersNCT05958615ACTIVE_NOT_RECRUITING
Obesity, Morbid
  • Reimagining Us in the Context of Bariatric Surgery (ReConnect)
Larissa McGarrity, Ph.D.INTERVENTIONAL
Trigeminal Evoked Responses to Improve RhizotomyNCT05738096RECRUITING
Trigeminal Neuralgia
Rhizotomy
  • TSEP + rhizotomy surgery
  • TSEPs recording only
University of MinnesotaINTERVENTIONAL
Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWINCT05377242ACTIVE_NOT_RECRUITING
Gulf War Illness
  • Curcumin
  • Resveratrol
  • Stinging Nettle
University of Alabama at BirminghamINTERVENTIONAL
An Observational Study to Evaluate Effectiveness and Safety of Upadacitinib in Chinese Adult Participants With Moderate to Severely Active Ulcerative Colitis (UC)NCT06838845RECRUITING
Ulcerative Colitis
N/AAbbVieOBSERVATIONAL
Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 DiabetesNCT04916470COMPLETED
Heart Failure With Preserved Ejection Fraction (HFpEF) and Diabetes Mellitus, Type 2
  • Semaglutide
  • Placebo (Semaglutide)
Novo Nordisk A/SINTERVENTIONAL
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung CancerNCT04181060RECRUITING
Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
Recurrent Lung Non-Squamous Non-Small Cell Carcinoma
Stage IIIB Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
  • Bevacizumab
  • Biospecimen Collection
  • Computed Tomography
  • Echocardiography Test
  • Magnetic Resonance Imaging
  • Multigated Acquisition Scan
  • Osimertinib
National Cancer Institute (NCI)INTERVENTIONAL
Pilot Clinical Evaluation of a Microwave Imaging System for Breast Cancer DetectionNCT05757427COMPLETED
Breast Cancer
  • Wavelia #2
MVG Industries SASINTERVENTIONAL
Zinc and Iron Absorption From Common Beans in Young Adult WomenNCT06327529RECRUITING
Zinc Absorption
Iron Absorption
  • SER 118
  • LMP 1001
  • LPA 586
  • KAT B1
University of California, DavisINTERVENTIONAL
A Weight Maintenance Program Promoting Fat Loss in Pregnancy in Women With ObesityNCT04731688COMPLETED
Gestational Weight Gain
Obesity
  • Weight Maintenance Group
Pennington Biomedical Research CenterINTERVENTIONAL
Cervical Intraepithelial Neoplasia Screening Using Liquid-Based Pap Smear Among Egyptian WomenNCT07250841COMPLETED
Cervical Intraepithelial Neoplasia
Cervical Cancer (Early Detection)
  • Liquid-Based Pap Smear (LBC)
Kasr El Aini HospitalOBSERVATIONAL
Web-administered STAIR for Patients on Behavioral Health WaitlistsNCT06431022ACTIVE_NOT_RECRUITING
Post Traumatic Stress Disorder
  • webSTAIR
  • CHW coaching
Boston Medical CenterINTERVENTIONAL
Neural Bases of MotivationNCT07251816NOT_YET_RECRUITING
Healthy Volunteers
Motivation
Action
  • Cortico-cortical paired-associative stimulation (ccPAS)
  • Bifocal transcranial alternating current stimulation (tACS)
  • Combining transcranial temporal interference stimulation (tTIS) and oscillatory TMS
  • Transcranial direct current stimulation (tDCS)
  • Transcutaneous vagal nerve stimulation (tVNS)
  • MRI
  • MEG
  • Pupillometry
  • Neuropsychological scales
  • EEG
Hospices Civils de LyonINTERVENTIONAL
Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)NCT05026138RECRUITING
Human Papillomavirus
N/ANational Institute of Allergy and Infectious Diseases (NIAID)OBSERVATIONAL
The Early Impact of Postoperative Bracing on Pain and Quality of Life Following Posterior Instrumented Fusion for Lumbar Degenerative ConditionsNCT02773134COMPLETED
Lumbar Degenerative Conditions
  • Brace Group
  • Control Group
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de MontrealINTERVENTIONAL
The AHA Oneida StudyNCT07139132RECRUITING
Oneida Nation Members
  • Health Wellness Coaching
  • Carotid ultrasound
  • School-age nutritional education program
  • Cognitive Testing
  • Blood work
University of Wisconsin, MadisonINTERVENTIONAL
Efficacy of a Multimodal Physiotherapy Program and Mobile-App Guided Meditation in Adults With Frequent or Chronic Tension-Type HeadacheNCT07240532NOT_YET_RECRUITING
Tension-Type Headache
Chronic Tension-type Headache
Frequent Episodic Tension-Type Headache
  • Multimodal Physiotherapy for Tension-Type Headache
  • Guided Meditation Using Insight Timer App
Universidad de GranadaINTERVENTIONAL
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)NCT06507748NOT_YET_RECRUITING
Neurofibromatosis Type 1
  • AlgometRx Nociometer
National Cancer Institute (NCI)INTERVENTIONAL
Spinal Versus General Anesthesia and Inflammatory Response Measured by Delta Neutrophil Index in Total Knee Arthroplasty: An Observational StudyNCT07214558COMPLETED
Inflammatory Response in Total Knee Arthroplasty
  • Routine Clinical Anesthesia Practice
Elazıg Fethi Sekin Sehir HastanesiOBSERVATIONAL
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric ParticipantsNCT05835310RECRUITING
Systemic Lupus Erythematosus
  • Anifrolumab
  • Placebo
AstraZenecaINTERVENTIONAL
Cognitive Screening and Multidomain Intervention Targeting Cognitive Decline in Type 2 Diabetes (The Brain Care Study)NCT07250789RECRUITING
Diabetes
Diabetes Mellitus Type 2
Type 2 Diabetes
Type 2 Diabetes Mellitus (T2DM)
Cognitive Impairment
Cognitive Decline
  • Multidomain Intervention Targeting Cognitive Decline
Steno Diabetes Center CopenhagenINTERVENTIONAL
Effects of Trancutaneous Auriculotemporal Nerve StimulationNCT07184190COMPLETED
Healthy
  • Trancutaneous Auriculotemporal Nerve Stimulation
University of Gran RosarioINTERVENTIONAL
Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNSNCT06553625RECRUITING
Parkinson Disease
Dystonia
Essential Tremor
Movement Disorders
  • Radiofrequency Ablation
Boston Scientific CorporationOBSERVATIONAL
A Study to Assess the Bioavailability of a New Tablet Formulation of Minzasolmin and the Effect of Food in Healthy ParticipantsNCT06533475COMPLETED
Healthy Participants
  • Minzasolmin tablet formulation under fasting condition
  • Minzasolmin Granules in capsule under fasting condition
  • Minzasolmin tablet formulation under fed condition
UCB Biopharma SRLINTERVENTIONAL
A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Prevention of Acute GastroenteritisNCT06592794RECRUITING
Acute Gastroenteritis
Norovirus Acute Gastroenteritis
  • mRNA-1403
  • Placebo
ModernaTX, Inc.INTERVENTIONAL
Brightline-2: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or BladderNCT05512377COMPLETED
Pancreatic Neoplasms
Solid Tumors
Biliary Tract Cancer
Lung Neoplasms
Bladder Cancer
  • brigimadlin
Boehringer IngelheimINTERVENTIONAL
A Study of TAK-771 in Japanese Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and Multifocal Motor Neuropathy (MMN)NCT05084053ACTIVE_NOT_RECRUITING
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Multifocal Motor Neuropathy (MMN)
  • TAK-771
TakedaINTERVENTIONAL
A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease AgitationNCT05557409COMPLETED
Agitation in Patients With Dementia of the Alzheimer's Type
Alzheimer Disease
Agitation
  • AXS-05
  • Placebo
Axsome Therapeutics, Inc.INTERVENTIONAL
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung CancerNCT05642195SUSPENDED
Non-Small Cell Lung Cancer
Non-Small Cell Lung Carcinoma
Carcinoma, Non-Small-Cell Lung
Carcinomas
  • Montanide (Registered Trademark) ISA-51 VG Adjuvant
  • H1299 Cell Lysates
  • N-803
  • Ventana PD-L1 (SP263 or SP142) assay
National Cancer Institute (NCI)INTERVENTIONAL
Effect of Anal Lift Exercise on Rehabilitation After Anal Fistula SurgeryNCT07250711NOT_YET_RECRUITING
Kegel Exercises
  • Kegel exercises
The Affiliated Hospital of Putian UniversityINTERVENTIONAL
Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALLNCT07250087RECRUITING
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
  • Asciminib
H. Lee Moffitt Cancer Center and Research InstituteINTERVENTIONAL
Tofacitinib in Juvenile Idiopathic ArthritisNCT07211932NOT_YET_RECRUITING
Juvenile Idiopathic Arthritis (JIA)
  • Tofacitinib
Consorci Sanitari de l'Alt Penedès i GarrafOBSERVATIONAL
Randomized Controlled Clinical Evaluation to Compare Vanguard Cruciate Retaining and AGC Total Condylar Knee ImplantsNCT01064063COMPLETED
Osteoarthritis
Rheumatoid Arthritis
Traumatic Arthritis
  • Vanguard CR
  • AGC knee
Zimmer BiometINTERVENTIONAL
Structured Handoff Using Intelligent Framework for Transitions TrialNCT07251907NOT_YET_RECRUITING
Electronic Medical Record
Transitions of Care
Physician Workflow
Artificial Intelligence (AI)
Large Language Model
  • LLM tool to draft handoff
University of PennsylvaniaINTERVENTIONAL
Posture Training for Middle SchoolersNCT06909747NOT_YET_RECRUITING
Musculoskeletal Pain
Postural; Defect
  • Posture Training
Amasya UniversityINTERVENTIONAL
INNODIA Family & Friends Early-Stage T1D Detection ProtocolNCT07118098RECRUITING
Type 1 Diabetes (T1D)
Pre Diabetes
N/AINNODIA iVZWOBSERVATIONAL
A Study of Lanadelumab in Children With Hereditary Angioedema (HAE) in Multiple CountriesNCT07251933NOT_YET_RECRUITING
Hereditary Angioedema (HAE)
  • No intervention
TakedaOBSERVATIONAL
Compare the Difference in Occlusal Force Distribution and Denture Retention Using 2 Different Denture Base Materials in Implant Retained OverdentureNCT07250503ACTIVE_NOT_RECRUITING
Edentulous Alveolar Ridge In Mandible
Complete Edentulism
Dental Implant
Attachments
Implant Retained Overdenture
Edentulous Mouth
  • Conventional acrylic resin denture
  • Flexible resin denture
Al-Azhar UniversityINTERVENTIONAL
Effectiveness of a Dual Program for Improving Sleep in Older Adults.NCT07251452ACTIVE_NOT_RECRUITING
Sleep
Gerontology
Physical Therapy
Cognitive
  • Otago programme
  • Otago programme + Cognifit
  • Control
University of Castilla-La ManchaINTERVENTIONAL
A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary FibrosisNCT06736990RECRUITING
Idiopathic Pulmonary Fibrosis
  • CAL101
  • Placebo
Calluna Pharma ASINTERVENTIONAL
Non-invasive Auricular Fiber Vagus Nerve Stimulation (afVNS) for Treatment of Autism Spectrum DisorderNCT06473623RECRUITING
Autism Spectrum Disorder
  • vagus nerve stimulation
NeuropixINTERVENTIONAL
PRetreatment MRI for OCcult Liver Metastasis Assessment In Pancreatic Ductal adenocarcinoMaNCT07252076RECRUITING
Pancreatic Ductal Adenocarcinoma
  • Contrast-enhanced MRI and DWI sequences
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOBSERVATIONAL
Serious Game for Improving Targeted Temperature Management Knowledge and Situational Awareness in Critical Care NursesNCT07239206NOT_YET_RECRUITING
Targeted Temperature Management
Nursing Education
Serious Game
Cardiac Arrest
  • Serious Game Intervention
  • Lecture-based Education
National Taiwan University Clinical Trial CenterINTERVENTIONAL
3D Biomimetic Spine Unit Model Through the Integration of Bioprinting and Transcriptomics (CDP-SUBT)NCT07250126RECRUITING
Degenrative Disc Disease
N/AI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioOBSERVATIONAL
Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical TrialNCT06274749RECRUITING
Healthy Volunteer
  • Urolithin A
  • Placebo
National Institute on Aging (NIA)INTERVENTIONAL
A Study to Evaluate the Efficacy and Safety of TTYP01 Tablets in Early Symptomatic Alzheimer's DiseaseNCT07252440RECRUITING
AD
Early Alzheimer's Disease
  • TTYP01 tables 60mg
  • TTYP01 tables 90mg
  • TTYP01 tables 0mg
Shanghai Auzone Biological Technology Co., Ltd.INTERVENTIONAL
Remineralization Capacity and Patient Satisfaction of Self-Assembling Peptide With Fluoride Versus Tooth Protective Coating With Surface Pre-Reacted Glass on White Spot LesionsNCT07086235COMPLETED
White Spot Lesions
  • self-assembling peptide
  • S-PRG Barrier Coat
Nahda UniversityINTERVENTIONAL
Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric CancerNCT03030404COMPLETED
Stomach Neoplasms
Stomach Cancer
Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)
Hereditary Diffuse Gastric Cancer (HDGC)
Familial Diffuse Gastric Cancer
N/ANational Cancer Institute (NCI)OBSERVATIONAL
Steroid Treatment for Elimination of Rebound Obstruction From Intranasal DecongestantsNCT07168148RECRUITING
Nasal Obstruction
Chronic Rhinitis
  • Oxymetazoline + Triamcinolone
Washington University School of MedicineINTERVENTIONAL
Supplement and Exercise Effects on Stationary Immunity and Health in Older AdultsNCT07251244RECRUITING
Aging
Older Adults
  • Group 1: Exercise + nutritional supplement (EXNS)
  • Group 2: Exercise + placebo nutritional supplement (EXPlaNS)
University of ValenciaINTERVENTIONAL
Functional vs Traditional Training in Older Women's HealthNCT05551000COMPLETED
Performance Enhancement
  • Experimental, comparator and control
Aalborg UniversityINTERVENTIONAL
Isometric Resistance Training and Dose-dependent Effects in Pre- and Hypertensive AdultsNCT07251920COMPLETED
Hypertension
Blood Pressure, High
  • Isometric resistance training
The University of NorthamptonINTERVENTIONAL
A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid TumorsNCT06533059RECRUITING
Cancer
Breast Cancer
Endometrial Cancer
Metastatic Cancer
Advanced Solid Tumor
  • ALTA2618
Alterome Therapeutics, Inc.INTERVENTIONAL
Phrenoesophageal Ligament Reconstruction With MeshNCT07251010NOT_YET_RECRUITING
Hiatus Hernia
Gastreoesophageal Reflux Disease
  • Phrenoesophageal Ligament Reconstruction with Mesh: A New Approach to Hiatal Hernia Repair (Alinasser's Technique)
  • Classic approach
Clinical Trial AseerINTERVENTIONAL
Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People Living With HIV Receiving Antiretroviral TherapyNCT06819176RECRUITING
Human Immunodeficiency Virus
  • Lenacapavir
National Institute of Allergy and Infectious Diseases (NIAID)INTERVENTIONAL
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)NCT07222332NOT_YET_RECRUITING
Diabetes Mellitus, Type 1
  • Baricitinib
  • Placebo
Eli Lilly and CompanyINTERVENTIONAL
Cold atmOspheric plaSMa Therapy Versus standArd Wound Care in Diabetic Foot and Venous Leg ulcerSNCT07251426NOT_YET_RECRUITING
Diabetic Foot Ulcer
Venous Leg Ulcer
  • COLD ATMOSPHERIC PLASMA
Olaf BakkerINTERVENTIONAL
A Study to Evaluate Safety and Anti-Tumor Activity of Eciskafusp Alfa (RO7284755) Alone or in Combination With Atezolizumab in Participants With Advanced and/or Metastatic Solid TumorsNCT04303858ACTIVE_NOT_RECRUITING
Solid Tumors
  • Eciskafusp Alfa
  • Atezolizumab
Hoffmann-La RocheINTERVENTIONAL
Observatory of Prolymphocytic Leukemia TNCT04411043RECRUITING
Prolymphocytic Leukemia
T-cell Leukemia
  • Molecular caracterization
French Innovative Leukemia OrganisationOBSERVATIONAL
A Study to Evaluate the Efficacy and Safety of QVM149 (Indacaterol Acetate / Glycopyrronium Bromide / Mometasone Furoate) Versus Salmeterol Xinafoate/Fluticasone Propionate in Children From 12 Years to Less Than 18 Years of Age With Asthma.NCT05776927NOT_YET_RECRUITING
Asthma
  • QVM149
  • Salmeterol Xinafoate / Fluticasone Propionate
  • Placebo to QVM149
  • Placebo to Salmeterol Xinafoate / Fluticasone Propionate
  • Run-In Medication
  • Rescue Medication
  • Concept 1 Device
  • Girohaler
Novartis PharmaceuticalsINTERVENTIONAL
Erector Spinae Plane Block in Lumbar Release SurgeryNCT04925882COMPLETED
Hernia Lumbar
Lumbar Canal Stenosis
Spinal Cord Compression
  • Erector spinae plane block
  • Erector spinae plane block
Clinique Saint Jean, FranceINTERVENTIONAL
Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk SurgeryNCT03271762ACTIVE_NOT_RECRUITING
Mitral Regurgitation
  • percutaneous mitral valve repair with MITRACLIP NT, MITRACLIP NTR/XTR, MITRACLIP G4NT/XT, MITRACLIP G4NTW/XTW
  • cardiac surgery
Nantes University HospitalINTERVENTIONAL
Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-IINCT06576427RECRUITING
Pulmonary Embolism
  • Vertex Pulmonary Embolectomy System
Jupiter EndovascularINTERVENTIONAL
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE TrialNCT06096844RECRUITING
Advanced Lung Non-Small Cell Carcinoma
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
  • Carboplatin
  • Computed Tomography
  • Magnetic Resonance Imaging
  • Nab-paclitaxel
  • Paclitaxel
  • Pembrolizumab
  • Pemetrexed
  • Positron Emission Tomography
  • Questionnaire Administration
National Cancer Institute (NCI)INTERVENTIONAL
Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)NCT06780111RECRUITING
Esophageal Squamous Cell Carcinoma
  • Pembrolizumab
  • I-DXd
  • Leucovorin
  • Levoleucovorin
  • 5-Fluorouracil (5-FU)
  • Oxaliplatin
Merck Sharp & Dohme LLCINTERVENTIONAL
Generation Healthy Kids: A Cluster-randomized Trial of a Multi-component, Multi-setting InterventionNCT05940675COMPLETED
Childhood Obesity
Well-Being, Psychological
Physical Inactivity
Sleep
Screen Time
Diet Habit
  • Food and Nutrition
  • Physical Activity (FitFirst)
  • Sleep and screen media
  • Community capacity building
University of CopenhagenINTERVENTIONAL
A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney DiseaseNCT05970172RECRUITING
Chronic Kidney Disease
Renal Anemia
  • Roxadustat
Astellas Pharma Global Development, Inc.INTERVENTIONAL
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast CancerNCT07102381RECRUITING
HER2-positive Breast Cancer
Breast Cancer
  • Zanidatamab
  • Paclitaxel
  • Docetaxel
  • Carboplatin
  • Trastuzumab
  • Pertuzumab
Jazz PharmaceuticalsINTERVENTIONAL
Comparison Between Emdogain and Amniotic Membrane as a Scaffold in Endodontic Regeneration of Immature Anterior TeethNCT07252167ACTIVE_NOT_RECRUITING
Non-vital Immature Anterior Teeth
  • Regenerative endodontic treatment with conventional blood clot technique.
  • regenerative endodontic treatment with emdogain.
  • regenerative endodontic treatment with amniotic membrane
Al-Azhar UniversityINTERVENTIONAL
A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal InsulinNCT07215312RECRUITING
Diabetes Mellitus, Type 2
  • LY3938577
  • Degludec
Eli Lilly and CompanyINTERVENTIONAL
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)NCT03407079RECRUITING
Healthy Volunteers
Overweight
  • Sucralose
  • Placebo
National Institute on Alcohol Abuse and Alcoholism (NIAAA)INTERVENTIONAL
Investigation of the Effectiveness of Short Wave Diathermy Treatment in Patients With Hand OsteoarthritisNCT06739096ACTIVE_NOT_RECRUITING
Hand Osteoarthritis
Osteoarthritis
  • Short Wave Diathermy
  • Exercise
  • Sham Short Wave Diathermy
Omer SezginINTERVENTIONAL
Pirtobrutinib and Mosunetuzumab for the Treatment of Relapsed/Refractory Grades 1-3A Follicular Lymphoma, PROMOTE-FL TrialNCT06948786RECRUITING
Grade 1 Follicular Lymphoma
Grade 2 Follicular Lymphoma
Grade 3a Follicular Lymphoma
Recurrent Follicular Lymphoma
Refractory Follicular Lymphoma
  • Pirtobrutinib
  • Mosunetuzumab
  • Biospecimen Collection
  • Biopsy Procedure
  • Computed Tomography
  • Positron Emission Tomography
  • Bone Marrow Aspiration
  • Bone Marrow Biopsy
  • Questionnaire Administration
University of WashingtonINTERVENTIONAL
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)NCT03486873RECRUITING
Solid Tumors
Hematologic Malignancies
  • Pembrolizumab
  • Standard of Care (SOC)
  • Lenvatinib
  • Olaparib
  • MK-4280
  • MK-4280A
Merck Sharp & Dohme LLCINTERVENTIONAL
Study Comparing EC-T Verses PCb in the Adjuvant Chemotherapy of Non-triple Negative Breast CancerNCT04193059ACTIVE_NOT_RECRUITING
Breast Cancer
  • Paclitaxel
  • Carboplatin
  • Epirubicin
  • Cyclophosphamide
  • Trastuzumab
  • Pertuzumab
  • Docetaxel
Fudan UniversityINTERVENTIONAL
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)NCT02861573RECRUITING
Metastatic Castration-Resistant Prostate Cancer
  • Pembrolizumab 200 mg
  • Olaparib 400 mg
  • Docetaxel 75 mg/m^2
  • Prednisone 5 mg
  • Enzalutamide 160 mg
  • Dexamethasone 8 mg
  • Olaparib 300 mg
  • Abiraterone acetate 1000 mg
  • Lenvatinib
  • Pembrolizumab/Vibostolimab coformulation
  • Carboplatin
  • Etoposide
  • Belzutifan 120mg
Merck Sharp & Dohme LLCINTERVENTIONAL
Elasticity of Structures Around the Ankle in Chronic Ankle InstabilityNCT06987435COMPLETED
Chronic Ankle Instability
N/AHacettepe UniversityOBSERVATIONAL
A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...NCT05621291RECRUITING
B-All
Acute Lymphoblastic Leukemia
  • NGS testing
National Cancer Institute (NCI)INTERVENTIONAL
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:NCT07186101RECRUITING
Ulcerative Colitis
  • LY4268989
  • Mirikizumab
  • LY4268989 Placebo
Eli Lilly and CompanyINTERVENTIONAL
Turkish Validation and Reliability of the John Hopkins In-Room Independence ScaleNCT07250243ENROLLING_BY_INVITATION
Independence
Hemiplegia
Paraplegia
Parkinson Disease
Polyneuropathy
Arthrosis
Amputation
Musculoskeletal Disease
  • In-room independence assessment
Sisli Hamidiye Etfal Training and Research HospitalOBSERVATIONAL
The Purpose of This Study is to Evaluate the Efficacy and Safety of 626 in the Treatment of SLENCT07185269RECRUITING
Systemic Lupus Erythematosus (SLE)
  • 626
  • 626
  • Placebo
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.INTERVENTIONAL
Effects of Energy Drinks on Cardiovascular EndpointsNCT07212803RECRUITING
Healthy Volunteers
Safety After Oral Intake
  • Energy Drink A + Placebo Capsule
  • Placebo Drink + Moxifloxacin Capsule
  • Placebo Drink + Caffeine Capsule
  • Placebo Drink + Placebo Capsule
  • Energy Drink B
  • Control Product + Taurine
  • Control Product + Caffeine + Taurine
  • Lower Dose Energy Drink A
University of the PacificINTERVENTIONAL
Perceptual Consequences of Cochlear Implant Electrode-neuron InterfacesNCT05867173RECRUITING
Deafness
  • Experimental Speech Processing Strategy
Massachusetts Eye and Ear InfirmaryINTERVENTIONAL
A Clinical Study on the Efficacy and Safety of Fasudil Hydrochloride Combined With Immunotherapy in the Treatment of Metastatic Castration-resistant Prostate CancerNCT07250542RECRUITING
Prostate Cancer
  • Fasudil hydrochloride combined with immunotherapy
baotai LiangINTERVENTIONAL
Impact of Pegfilgrastim on Trastuzumab Anti-tumor Effect and ADCC in Operable HER2+ Breast Cancer Breast CancerNCT03571633ACTIVE_NOT_RECRUITING
HER2-positive Breast Cancer
Operable Breast Cancer
  • Trastuzumab + Paclitaxel
  • Pegfilgrastim
Centre Leon BerardINTERVENTIONAL
A Phase 1, Randomized, Placebo-Controlled Safety and Tolerability Study Of Intravenous SBS-1000 in Healthy AdultsNCT05721287COMPLETED
Pain
Acute Pain
  • SBS-1000
  • Placebo
Sparian Biosciences, IncINTERVENTIONAL
Intestinal Bacteria and Ocular Inflammatory DiseaseNCT01859299COMPLETED
Uveitis
N/ANational Eye Institute (NEI)OBSERVATIONAL
Evaluation of Trop-2 ADC in Breast Cancer Patients With Brain Metastases: A Real-World StudyNCT07251868RECRUITING
Breast Cancer
Brain Metastases From Breast Cancer
Trop2
  • Sacituzumab Govitecan (SG)
Peking University Cancer Hospital & InstituteOBSERVATIONAL