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Study Title | NCT Number | Status | Conditions | Interventions | Sponsor | Study Type |
---|---|---|---|---|---|---|
An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer | NCT02632409 | ACTIVE_NOT_RECRUITING | Various Advanced Cancer |
| Bristol-Myers Squibb | INTERVENTIONAL |
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke | NCT05691244 | RECRUITING | Acute Ischemic Stroke Cerebral Stroke |
| Pharmazz, Inc. | INTERVENTIONAL |
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib | NCT04486833 | RECRUITING | Carcinoma, Non-Small Cell Lung |
| Genprex, Inc. | INTERVENTIONAL |
N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer | NCT07217496 | NOT_YET_RECRUITING | Metastatic Urothelial Carcinoma Urothelial Carcinoma Locally Advanced Urothelial Carcinoma Urothelial Cancer |
| Vadim S Koshkin | INTERVENTIONAL |
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) | NCT05254743 | RECRUITING | Chronic Lymphocytic Leukemia Leukemia, Lymphocytic Leukemia, B-cell Small Lymphocytic Lymphoma |
| Loxo Oncology, Inc. | INTERVENTIONAL |
Study of AZD2811 + Durvalumab in ES-SCLC | NCT04745689 | ACTIVE_NOT_RECRUITING | Small-Cell Lung Cancer |
| AstraZeneca | INTERVENTIONAL |
A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis | NCT06311682 | RECRUITING | Atopic Dermatitis |
| LEO Pharma | INTERVENTIONAL |
Nogapendekin Alfa Inbakicept for Advanced Non-Small Cell Lung Cancer | NCT03520686 | ACTIVE_NOT_RECRUITING | Non Small Cell Lung Cancer |
| ImmunityBio, Inc. | INTERVENTIONAL |
PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation | NCT05639751 | COMPLETED | Advanced Solid Tumor Metastatic Solid Tumor Non-small Cell Lung Cancers SMARCA4 Gene Mutation |
| Prelude Therapeutics | INTERVENTIONAL |
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2 | NCT06952530 | RECRUITING | Hypertension |
| Eli Lilly and Company | INTERVENTIONAL |
RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia Radiosurgery | NCT02708810 | ACTIVE_NOT_RECRUITING | Trigeminal Neuralgia |
| University of Alabama at Birmingham | INTERVENTIONAL |
A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3) | NCT06653153 | ACTIVE_NOT_RECRUITING | Alzheimer's Disease |
| Eli Lilly and Company | INTERVENTIONAL |
Is Our Microbiome a Predictor of Cardiac Risk | NCT02013284 | ENROLLING_BY_INVITATION | Coronary Artery Disease | N/A | Mayo Clinic | OBSERVATIONAL |
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid Tumors | NCT06804824 | RECRUITING | Advanced Solid Tumors |
| Vividion Therapeutics, Inc. | INTERVENTIONAL |
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart | NCT06935370 | RECRUITING | Heart Failure |
| Boehringer Ingelheim | INTERVENTIONAL |
Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive IDH-1 Mutant Glioma | NCT05484622 | RECRUITING | Astrocytoma Oligodendroglioma |
| Institut de Recherches Internationales Servier | INTERVENTIONAL |
Elbow Artery Embolization for Tennis Elbow | NCT05325242 | RECRUITING | Lateral Epicondylitis, Unspecified Elbow |
| Siddharth Padia, MD | INTERVENTIONAL |
Investigating the Impact of Obesity on Pubertal Development in Girls | NCT02583646 | RECRUITING | Obesity Puberty Normal Physiology | N/A | National Institute of Environmental Health Sciences (NIEHS) | OBSERVATIONAL |
Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple Sclerosis | NCT04480853 | RECRUITING | Multiple Sclerosis |
| Novartis Pharmaceuticals | INTERVENTIONAL |
A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer) | NCT05296798 | RECRUITING | Locally Advanced or Metastatic Breast Cancer |
| Hoffmann-La Roche | INTERVENTIONAL |
An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 Trial | NCT06999798 | RECRUITING | Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Locally Advanced Breast Carcinoma |
| Mayo Clinic | INTERVENTIONAL |
Cancer Within a Pandemic: A Telemental Health Intervention | NCT04659993 | TERMINATED | Cancer Survivorship Depression, Anxiety |
| Wake Forest University Health Sciences | INTERVENTIONAL |
Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma | NCT06563102 | RECRUITING | Mild Asthma |
| AstraZeneca | INTERVENTIONAL |
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide | NCT06897475 | RECRUITING | Type 2 Diabetes |
| Eli Lilly and Company | INTERVENTIONAL |
QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer | NCT03022825 | ACTIVE_NOT_RECRUITING | Bladder Cancer |
| ImmunityBio, Inc. | INTERVENTIONAL |
Integrative Medicine in Pain Management in Sickle Cell Disease | NCT05045820 | ACTIVE_NOT_RECRUITING | Sickle Cell Disease Pain Acupuncture Quantitative Sensory Testing Magnetic Resonance Imaging Circulating Biomarkers Electroencephalography Functional Near-infrared Spectroscopy |
| Indiana University | INTERVENTIONAL |
An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus | NCT05352919 | ENROLLING_BY_INVITATION | Systemic Lupus Erythematosus (SLE) |
| Biogen | INTERVENTIONAL |
A PHASED, PROSPECTIVE, MULTI-CENTER STUDY OF THE ELITA SYSTEM | NCT05713253 | TERMINATED | Refractive Error |
| Johnson & Johnson Surgical Vision, Inc. | INTERVENTIONAL |
Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation | NCT06427811 | ACTIVE_NOT_RECRUITING | Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase |
| Novartis Pharmaceuticals | INTERVENTIONAL |
Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia | NCT04652726 | COMPLETED | Familial Hypercholesterolemia - Heterozygous |
| Novartis Pharmaceuticals | INTERVENTIONAL |
Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine | NCT05738213 | ACTIVE_NOT_RECRUITING | Migraine |
| Washington University School of Medicine | INTERVENTIONAL |
Expanded Access [11C] Methionine PET Imaging | NCT05511714 | AVAILABLE | Central Nervous System Tumor Head and Neck Neoplasms |
| St. Jude Children's Research Hospital | EXPANDED_ACCESS |
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers | NCT05882058 | RECRUITING | Small Cell Lung Carcinoma Neuroendocrine Neoplasms Extra-pulmonary Neuroendocrine Carcinoma |
| Boehringer Ingelheim | INTERVENTIONAL |
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee | NCT07153471 | RECRUITING | Osteoarthritis |
| Eli Lilly and Company | INTERVENTIONAL |
E-mails to Nudge Safer and Better-Informed Prescribing of Risky Drugs | NCT06443385 | ACTIVE_NOT_RECRUITING | Opioid Prescribing Prescription Drug Misuse |
| Columbia University | INTERVENTIONAL |
S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP | NCT06188702 | RECRUITING | MTAP-deleted Solid Tumors |
| Servier Bio-Innovation LLC | INTERVENTIONAL |
Left Bundle Branch Area Pacing (LBBAP) PMCF Study | NCT07217392 | RECRUITING | Bradycardia Right Ventricular Pacing Heart Failure Atrial Fibrillation (AF) Cardiac Disease Left Bundle Branch Area Pacing Conduction System Pacing |
| Abbott Medical Devices | INTERVENTIONAL |
N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastoma | NCT06061809 | ACTIVE_NOT_RECRUITING | Glioblastoma |
| ImmunityBio, Inc. | INTERVENTIONAL |
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3) | NCT05716100 | RECRUITING | Focal Onset Seizures |
| Xenon Pharmaceuticals Inc. | INTERVENTIONAL |
Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) | NCT07149428 | NOT_YET_RECRUITING | Respiratory Tract Infection Smell Disorder Influenza Rhinosinusitis COVID-19 Depression Parosmia Hyposomia Normosomia Anosmia | N/A | National Institute on Deafness and Other Communication Disorders (NIDCD) | OBSERVATIONAL |
Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus | NCT04370795 | ENROLLING_BY_INVITATION | Severe Combined Immune Deficiency (SCID) |
| National Institute of Allergy and Infectious Diseases (NIAID) | INTERVENTIONAL |
Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) | NCT07027839 | RECRUITING | Alcohol Use Disorder |
| National Institute of Mental Health (NIMH) | INTERVENTIONAL |
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC) | NCT07217717 | NOT_YET_RECRUITING | Pancreatic Ductal Adenocarcinoma (PDAC) |
| SOFIE | INTERVENTIONAL |
A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease | NCT07190196 | RECRUITING | Immunoglobulin G4 Related Disease |
| Sanofi | INTERVENTIONAL |
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation | NCT03856216 | TERMINATED | Acute Lymphoblastic Leukemia B Acute Lymphoblastic Leukemia Lymphocytic Neoplasm Lymphoma |
| M.D. Anderson Cancer Center | INTERVENTIONAL |
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation | NCT04449874 | ACTIVE_NOT_RECRUITING | Non-Small Cell Lung Cancer Colorectal Cancer Advanced Solid Tumors |
| Genentech, Inc. | INTERVENTIONAL |
Clinical Trial of Ablation Therapy in Participants With Intermediate-Risk Non-Muscle Invasive Papillary Bladder Cancer | NCT06829823 | NOT_YET_RECRUITING | Non-muscle Invasive Bladder Cancer (NMIBC) |
| ImmunityBio, Inc. | INTERVENTIONAL |
Genetic Analysis of Uncommon Disease Presentations in Non-US Populations | NCT06595940 | RECRUITING | Undiagnosed Diseases Rare Diseases | N/A | National Human Genome Research Institute (NHGRI) | OBSERVATIONAL |
A Study of LY4175408 in Participants With Advanced Cancer | NCT07046923 | RECRUITING | Carcinoma, Non-Small-Cell Lung Small Cell Lung Carcinoma Endometrial Neoplasms Neoplasm Metastasis Triple Negative Breast Cancer |
| Eli Lilly and Company | INTERVENTIONAL |
L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML | NCT06788756 | RECRUITING | Acute Myeloid Leukaemia (AML) |
| Moleculin Biotech, Inc. | INTERVENTIONAL |
The GRoceries Aimed at Increasing Nutrition Study | NCT07167004 | RECRUITING | Type 2 Diabetes Type II Diabetes Mellitus Type II Diabetes Pre-diabetes Pre-diabetic Pre-diabetic State Type 2 Diabetes Mellitus (T2DM) Type 2 Diabetes Mellitus Type 2 Diabetes (T2DM) |
| University of Pennsylvania | INTERVENTIONAL |
Project: Every Child for Younger Patients With Cancer | NCT02402244 | RECRUITING | Adrenal Gland Pheochromocytoma Carcinoma In Situ Central Nervous System Neoplasm Childhood Immature Teratoma Childhood Kidney Neoplasm Childhood Langerhans Cell Histiocytosis Childhood Mature Teratoma Congenital Mesoblastic Nephroma Desmoid Fibromatosis Ganglioneuroma Lymphoproliferative Disorder Malignant Neoplasm Malignant Solid Neoplasm Melanocytic Neoplasm Myeloproliferative Neoplasm Neoplasm of Uncertain Malignant Potential Neuroendocrine Neoplasm Stromal Neoplasm |
| Children's Oncology Group | OBSERVATIONAL |
Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias | NCT05509582 | ENROLLING_BY_INVITATION | Immune Mediated Anemia Immune Mediated Thrombocytopenia Chronic GVHD |
| National Heart, Lung, and Blood Institute (NHLBI) | INTERVENTIONAL |
Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam | NCT05386680 | COMPLETED | Spinal Muscular Atrophy |
| Novartis Pharmaceuticals | INTERVENTIONAL |
LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF) | NCT05321420 | ACTIVE_NOT_RECRUITING | Idiopathic Pulmonary Fibrosis |
| PureTech | INTERVENTIONAL |
A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy | NCT06769048 | RECRUITING | Geographic Atrophy |
| Boehringer Ingelheim | INTERVENTIONAL |
Optimization of Commissural Alignment During Transcatheter Aortic Valve Implantation With Evolut FX+ | NCT07217691 | NOT_YET_RECRUITING | Aortic Stenosis Trans-catheter Aortic Valve Implantation Commissural Alignment |
| Oslo University Hospital | INTERVENTIONAL |
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan | NCT00341874 | ENROLLING_BY_INVITATION | Hearing Disorder | N/A | National Institute on Deafness and Other Communication Disorders (NIDCD) | OBSERVATIONAL |
ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours | NCT06597721 | RECRUITING | Advanced Solid Tumor |
| Adcendo ApS | INTERVENTIONAL |
NHLBI-Emory Advanced Cardiac CT Reconstruction | NCT05372627 | NOT_YET_RECRUITING | Structural Heart Disease | N/A | National Heart, Lung, and Blood Institute (NHLBI) | OBSERVATIONAL |
Assessment of a Fruit and Vegetable Prescription Program for Children | NCT04767282 | COMPLETED | Exposure to Fruit and Vegetable Prescription Program |
| Michigan State University | INTERVENTIONAL |
A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy Adults | NCT05703607 | RECRUITING | Shingles Herpes Zoster Infection Human |
| Pfizer | INTERVENTIONAL |
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors | NCT05954312 | RECRUITING | Advanced Solid Tumors |
| Vividion Therapeutics, Inc. | INTERVENTIONAL |
Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy | NCT07186192 | RECRUITING | Hematologic Malignancies |
| City of Hope Medical Center | INTERVENTIONAL |
A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD) | NCT06450639 | RECRUITING | Duchenne Muscular Dystrophy |
| Hoffmann-La Roche | INTERVENTIONAL |
Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE) | NCT06041503 | NOT_YET_RECRUITING | Adenocarcinoma of the Bladder Squamous Cell Carcinoma of the Bladder Testicular Germ Cell Tumors |
| National Cancer Institute (NCI) | INTERVENTIONAL |
The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary Study | NCT04818034 | COMPLETED | Cystinuria |
| University of California, San Francisco | INTERVENTIONAL |
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis | NCT07217587 | NOT_YET_RECRUITING | Myasthenia Gravis |
| Janssen Research & Development, LLC | INTERVENTIONAL |
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer | NCT06991738 | NOT_YET_RECRUITING | Thyroid Cancer |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | INTERVENTIONAL |
STEMVAC in Patients With Early Stage Triple Negative Breast Cancer | NCT05455658 | ACTIVE_NOT_RECRUITING | Anatomic Stage IB Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage IIA Breast Cancer AJCC v8 Anatomic Stage IIB Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IIIA Breast Cancer AJCC v8 Anatomic Stage IIIB Breast Cancer AJCC v8 Anatomic Stage IIIC Breast Cancer AJCC v8 Prognostic Stage IB Breast Cancer AJCC v8 Prognostic Stage II Breast Cancer AJCC v8 Prognostic Stage IIA Breast Cancer AJCC v8 Prognostic Stage IIB Breast Cancer AJCC v8 Prognostic Stage III Breast Cancer AJCC v8 Prognostic Stage IIIA Breast Cancer AJCC v8 Prognostic Stage IIIB Breast Cancer AJCC v8 Prognostic Stage IIIC Breast Cancer AJCC v8 Triple-Negative Breast Carcinoma |
| University of Washington | INTERVENTIONAL |
Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression | NCT03507608 | COMPLETED | Prostate Cancer |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | INTERVENTIONAL |
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC) | NCT06117774 | RECRUITING | Limited Stage Small Cell Lung Cancer Small Cell Lung Cancer |
| Amgen | INTERVENTIONAL |
Prospective Evaluation of Silk Fibroin Incision Dressings in ACL Reconstruction | NCT07217613 | NOT_YET_RECRUITING | Anterior Cruciate Ligament Reconstruction |
| NYU Langone Health | INTERVENTIONAL |
SMART-r: Substance Monitoring and Active Relapse Tracking Repository | NCT06676059 | RECRUITING | Alcoholism Substance-Related Disorders | N/A | National Institute on Drug Abuse (NIDA) | OBSERVATIONAL |
An Extension Study of Subcutaneous Secukinumab in Patients With Juvenile Psoriatic Arthritis (JPsA) and Enthesitis Related Arthritis (ERA) | NCT03769168 | COMPLETED | Juvenile Psoriatic Arthritis Enthesitis Related Arthritis |
| Novartis Pharmaceuticals | INTERVENTIONAL |
A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment | NCT05889091 | RECRUITING | Head and Neck Squamous Cell Carcinoma |
| Memorial Sloan Kettering Cancer Center | INTERVENTIONAL |
A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats | NCT06049797 | ACTIVE_NOT_RECRUITING | Hot Flashes |
| Astellas Pharma Global Development, Inc. | OBSERVATIONAL |
A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid Arthritis | NCT06028438 | COMPLETED | Arthritis, Rheumatoid |
| Janssen Research & Development, LLC | INTERVENTIONAL |
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002) | NCT06077760 | RECRUITING | Non-small Cell Lung Cancer |
| Merck Sharp & Dohme LLC | INTERVENTIONAL |
Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological Involvement | NCT06923072 | RECRUITING | Kohlmeier-Degos Disease Malignant Atrophic Papulosis Degos Disease Papulosis, Malignant Atrophic |
| National Heart, Lung, and Blood Institute (NHLBI) | INTERVENTIONAL |
Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation | NCT02669251 | ACTIVE_NOT_RECRUITING | Chronic Graft vs Host Disease Chronic Graft-Versus-Host Disease Bronchiolitis Obliterans Syndrome |
| National Cancer Institute (NCI) | INTERVENTIONAL |
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) | NCT07169630 | RECRUITING | Alzheimer s Disease Mild Cognitive Impairment Healthy |
| National Institute of Mental Health (NIMH) | INTERVENTIONAL |
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine | NCT07018700 | RECRUITING | Episodic Migraine |
| Merz Therapeutics GmbH | INTERVENTIONAL |
Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study | NCT04593277 | ACTIVE_NOT_RECRUITING | Clinical Stage I Cutaneous Melanoma AJCC v8 Clinical Stage II Cutaneous Melanoma AJCC v8 Clinical Stage III Cutaneous Melanoma AJCC v8 Hematopoietic and Lymphoid Cell Neoplasm Invasive Malignant Neoplasm Leukemia Lymphoma Malignant Solid Neoplasm Sarcoma Stage I Colorectal Cancer AJCC v8 Stage II Colorectal Cancer AJCC v8 Stage III Colorectal Cancer AJCC v8 Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Thyroid Gland Carcinoma |
| Fred Hutchinson Cancer Center | INTERVENTIONAL |
A Study of Elranatamab (PF-06863135) in Chinese Participants With Refractory Multiple Myeloma. | NCT05228470 | ACTIVE_NOT_RECRUITING | Elranatamab Myeloma Multiple Myeloma Relapsed Multiple Myeloma Refractory Multiple Myeloma PF-06863135 BCMA Bispecific Bispecific Antibody BCMA-CD3 Bispecific MagnetisMM-8 |
| Pfizer | INTERVENTIONAL |
A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants | NCT05963984 | COMPLETED | Metastatic Breast Cancer Locally Advanced Breast Cancer Breast Cancer |
| Carrick Therapeutics Limited | INTERVENTIONAL |
Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02) | NCT06596694 | RECRUITING | Gastrointestinal Cancer |
| Merck Sharp & Dohme LLC | INTERVENTIONAL |
Treating Pain in Children With Cancer: Pain Buddy | NCT03384134 | COMPLETED | Cancer |
| University of California, Irvine | INTERVENTIONAL |
Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma | NCT06876142 | RECRUITING | Multiple Myeloma Relapsed and/or Refractory Multiple Myeloma (RRMM) |
| National Cancer Institute (NCI) | INTERVENTIONAL |
TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure | NCT03296813 | COMPLETED | Heart Failure |
| Duke University | INTERVENTIONAL |
Fluid Status of ESRD Patients Undergoing Dialysis | NCT07217470 | RECRUITING | ESRD (End Stage Renal Disease) | N/A | HemoCept Inc. | OBSERVATIONAL |
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis | NCT06096779 | RECRUITING | Hepatocellular Carcinoma |
| Genentech, Inc. | INTERVENTIONAL |
SAGE LEAF 2: An Online Program to Reduce Dementia Caregiver Burden | NCT06708182 | RECRUITING | Caregiving Stress Caregiver Burden |
| Northwestern University | INTERVENTIONAL |
A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal Impairment | NCT07104162 | RECRUITING | Bacterial Infections |
| Qpex Biopharma, Inc. | INTERVENTIONAL |
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC | NCT06788990 | RECRUITING | Metastatic Head and Neck Squamous Cell Carcinoma Recurrent Head and Neck Squamous Cell Carcinoma |
| Bicara Therapeutics | INTERVENTIONAL |
Mitigating the Disinhibiting Effects of Alcohol With Transcranial Magnetic Stimulation | NCT07188376 | NOT_YET_RECRUITING | Alcohol Risk Behaviors |
| Michael J. Wesley, PhD | INTERVENTIONAL |
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma | NCT06654050 | NOT_YET_RECRUITING | Mesothelioma Malignant Mesothelioma (MM) Early-stage Mesothelioma Subclinical Mesothelioma BRCA1-Associated Protein-1 (BAP1) Mutations Early-stage BAP1-associated Malignancies |
| National Cancer Institute (NCI) | INTERVENTIONAL |
A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008) | NCT03976362 | ACTIVE_NOT_RECRUITING | Carcinoma, Squamous Cell, Non-small-cell Lung |
| Merck Sharp & Dohme LLC | INTERVENTIONAL |
Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease | NCT04795466 | TERMINATED | Mild Cognitive Impairment Alzheimer Disease |
| Novartis Pharmaceuticals | INTERVENTIONAL |
[Trial of device that is not approved or cleared by the U.S. FDA] | NCT06903351 | WITHHELD | N/A | N/A | [Redacted] | N/A |