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Study TitleNCT NumberStatusConditionsInterventionsSponsorStudy Type
Pilot Study to Evaluate the Efficacy and Safety of Xvie Delivered Into the Scalp by Microneedling in Women With Self-perceived Thinning HairNCT07221773ENROLLING_BY_INVITATION
Hair Thinning
  • XVIE
Restore Biologics Holdings, Inc. dba XtresséINTERVENTIONAL
Platelet Volunteers, Longitudinal and Multi-omic StudyNCT07137429NOT_YET_RECRUITING
Thrombosis
N/ANational Heart, Lung, and Blood Institute (NHLBI)OBSERVATIONAL
A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus NephritisNCT04221477ACTIVE_NOT_RECRUITING
Lupus Nephritis
  • Obinutuzumab
  • MMF
  • Prednisone
  • Placebo
  • Methylprednisolone
  • Acetaminophen
  • Diphenhydramine
Hoffmann-La RocheINTERVENTIONAL
Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)NCT07225439NOT_YET_RECRUITING
Non Hodgkin Lymphoma
B-cell Non Hodgkin Lymphoma
Diffuse Large B Cell Lymphoma
High-grade B-cell Lymphoma
Primary Mediastinal Large B Cell Lymphoma
Follicular Lymphoma
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Marginal Zone Lymphoma
Mantle Cell Lymphoma
  • Allogeneic NK cells
  • Rituximab
  • Tafasitamab
  • Interleukin-2
  • Fludarabine/cyclophosphamide
Paolo Caimi, MDINTERVENTIONAL
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.NCT06247995RECRUITING
Breast Cancer
  • [68Ga]Ga-NeoB
  • [177Lu]Lu-NeoB
  • Capecitabine
Novartis PharmaceuticalsINTERVENTIONAL
Personalized NK Cell Therapy in CBTNCT02727803RECRUITING
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Acute Biphenotypic Leukemia
Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia in Remission
Acute Myeloid Leukemia With Myelodysplasia-Related Changes
Acute Myeloid Leukemia With Variant MLL Translocations
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
Chemotherapy-Related Leukemia
Chronic Myelomonocytic Leukemia
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
ISS Stage II Plasma Cell Myeloma
ISS Stage III Plasma Cell Myeloma
Myelodysplastic Syndrome
Myelodysplastic Syndrome With Excess Blasts
Myelodysplastic Syndrome With Gene Mutation
Myelodysplastic/Myeloproliferative Neoplasm
Previously Treated Myelodysplastic Syndrome
Recurrent Acute Myeloid Leukemia
Recurrent Adult Acute Myeloid Leukemia
Recurrent Hodgkin Lymphoma
Recurrent Non-Hodgkin Lymphoma
Refractory Acute Lymphoblastic Leukemia
Refractory Adult Acute Lymphoblastic Leukemia
Secondary Acute Myeloid Leukemia
Therapy-Related Myelodysplastic Syndrome
  • Allogeneic Natural Killer Cell Line NK-92
  • Anti-Thymocyte Globulin
  • Busulfan
  • Clofarabine
  • Cyclophosphamide
  • Fludarabine Phosphate
  • Laboratory Biomarker Analysis
  • Melphalan
  • Rituximab
  • Total-Body Irradiation
  • Umbilical Cord Blood Transplantation
M.D. Anderson Cancer CenterINTERVENTIONAL
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesNCT06904066RECRUITING
Malignancy, Hematologic
Neoplasms, Hematologic
Neoplasms, Hematopoietic
Blood Cancer
Hematological Neoplasms
Hematopoietic Malignancies
Dysmyelopoietic Syndromes
Hematopoetic Myelodysplasia
Myeloid Leukemia, Acute
Nonlymphoblastic Leukemia, Acute
Leukemia, Lymphocytic, Acute
  • aldesleukin
  • cyclophosphamide
  • fludarabine phosphate
  • Individual Patient TCR-Transduced PBL
  • TruSight Oncology (TSO) 500
National Cancer Institute (NCI)INTERVENTIONAL
A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)NCT01154374COMPLETED
Diabetic Foot Ulcers
  • MEBO Wound Ointment
  • Standard of Care (sterile saline moistened gauze)
Skingenix, Inc.INTERVENTIONAL
Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive ImpairmentNCT06031259ACTIVE_NOT_RECRUITING
Hunter Syndrome
  • Idursulfase-IT
  • Elaprase
TakedaINTERVENTIONAL
Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA)NCT05263934ACTIVE_NOT_RECRUITING
Eosinophilic Granulomatosis With Polyangiitis
  • Depemokimab
  • Mepolizumab
  • Placebo matching mepolizumab
  • Placebo matching depemokimab
GlaxoSmithKlineINTERVENTIONAL
Building and Sustaining Exercise Habits for Adults With Type 1 DiabetesNCT06967701RECRUITING
Type 1 Diabetes (T1D)
Latent Autoimmune Diabetes in Adult (LADA)
Pancreatitis
  • Exercise program
  • Self-monitoring
Yale UniversityINTERVENTIONAL
Effect of Text Message Reminders on M-ISI Score After Prostate SurgeryNCT07071207RECRUITING
Incontinence, Urinary Stress
Prostate Cancer
Benign Prostate Hyperplasia
  • Text message reminders
University of RochesterINTERVENTIONAL
ABT-888 With Modified FOLFOX6 in Patients With Metastatic Pancreatic CancerNCT01489865COMPLETED
Metastatic Pancreatic Cancer
  • ABT-888
  • mFOLFOX-6
Georgetown UniversityINTERVENTIONAL
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric PatientsNCT05711667ACTIVE_NOT_RECRUITING
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
  • Biospecimen Collection
  • Letermovir
Children's Oncology GroupINTERVENTIONAL
Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement DisordersNCT06848530NOT_YET_RECRUITING
Movement Disorders
  • Prescribed Medications
  • Deep brain stimulation adjustment
University of PennsylvaniaINTERVENTIONAL
Characterization of Hyperpolarized Pyruvate MRI ReproducibilityNCT02421380RECRUITING
Malignant Solid Tumors
  • Hyperpolarized Pyruvate
Memorial Sloan Kettering Cancer CenterINTERVENTIONAL
CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment.NCT04814654COMPLETED
Hiv
  • CHALO! 2.0
  • Attention-matched control (AMC)
  • Digital coupon only (DCO)
Albert Einstein College of MedicineINTERVENTIONAL
Detoxification of the Liver In PSC (Dolphin)NCT05835505RECRUITING
Primary Sclerosing Cholangitis
  • BRS201
  • Placebo
Brigham and Women's HospitalINTERVENTIONAL
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC TrialNCT06770582RECRUITING
Non-Muscle Invasive Bladder Urothelial Carcinoma
Recurrent Non-Muscle Invasive Bladder Urothelial Carcinoma
Stage I Bladder Cancer AJCC v8
  • Biospecimen Collection
  • Cisplatin
  • Computed Tomography
  • Fluorouracil
  • Gemcitabine
  • Magnetic Resonance Imaging
  • Mitomycin
  • Pembrolizumab
  • Questionnaire Administration
  • Radiation Therapy
National Cancer Institute (NCI)INTERVENTIONAL
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide RibosideNCT05245903RECRUITING
Alzheimer Disease
Dementia Alzheimers
Dementia
Cognitive Impairment
Mild Cognitive Impairment
Neurodegenerative Diseases
Neurocognitive Disorders
Neurocognitive Dysfunction
Cognitive Dysfunction
Mental Disorder
  • Emerald Device Monitoring
Mclean HospitalOBSERVATIONAL
A Trial to Learn if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone LymphomaNCT06149286RECRUITING
Relapsed/Refractory Follicular Lymphoma
Marginal Zone Lymphoma (MZL)
  • Odronextamab
  • Lenalidomide
  • Rituximab
Regeneron PharmaceuticalsINTERVENTIONAL
EDEN Intracardiac Electrogram Recording and Classifying SystemNCT07137455NOT_YET_RECRUITING
Ventricular Arrhythmia
  • EDEN Intracardiac Electrogram Recording and Classifying System
National Heart, Lung, and Blood Institute (NHLBI)INTERVENTIONAL
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C MutationNCT06252649RECRUITING
Metastatic Colorectal Cancer
  • FOLFIRI Regimen
  • Sotorasib
  • Panitumumab
  • Bevacizumab-awwb
AmgenINTERVENTIONAL
A Phase 3, Open-label, Crossover Study to Evaluate Self-administration of Rozanolixizumab by Study Participants With Generalized Myasthenia Gravis (gMG)NCT05681715COMPLETED
Generalized Myasthenia Gravis
  • Rozanolixizumab
UCB Biopharma SRLINTERVENTIONAL
Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic LeukemiaNCT02877303RECRUITING
B Acute Lymphoblastic Leukemia
B Lymphoblastic Lymphoma
  • Blinatumomab
  • Cyclophosphamide
  • Cytarabine
  • Dexamethasone
  • Doxorubicin Hydrochloride
  • Inotuzumab Ozogamicin
  • Laboratory Biomarker Analysis
  • Mercaptopurine
  • Methotrexate
  • Ofatumumab
  • Prednisone
  • Rituximab
  • Vincristine Sulfate
M.D. Anderson Cancer CenterINTERVENTIONAL
Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene TherapyNCT06100887ACTIVE_NOT_RECRUITING
Duchenne Muscular Dystrophy
  • Sevasemten Dose 1
  • Sevasemten Dose 2
  • Sevasemten Dose 3
  • Placebo
Edgewise Therapeutics, Inc.INTERVENTIONAL
Examining Whether Project Support WorksNCT06963554RECRUITING
Parent-Child Relations
Parenting Self Efficacy
Child Mental Health
  • Project Support
  • Case Management Services
Medical University of South CarolinaINTERVENTIONAL
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.NCT06372145RECRUITING
Relapsing Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Progressive Relapsing Multiple Sclerosis
  • Tolebrutinib
  • Placebo
  • Teriflunomide
SanofiINTERVENTIONAL
Laparoscopic Transversus Abdominis Plane (TAP) Block to Reduce Post-operative OpioidsNCT04655339WITHDRAWN
Opioid Use
  • Bilateral abdominal Lap-TAP
Baylor Research InstituteINTERVENTIONAL
STEP Together: An Effectiveness-Implementation Study of Social Incentives and Physical ActivityNCT04942535COMPLETED
Physical Activity
  • Social Incentive Gamification
  • Social Goals through Incentives to Charity
  • Daily Performance Feedback
Abramson Cancer Center at Penn MedicineINTERVENTIONAL
Observational Study of Advanced Data Analytics in Genetic ConditionsNCT05657405RECRUITING
Genetic Conditions
N/ANational Human Genome Research Institute (NHGRI)OBSERVATIONAL
Phase 2 Study of SAR444656 in Adult Participants With Moderate to Severe Atopic DermatitisNCT06058156ACTIVE_NOT_RECRUITING
Atopic Dermatitis
  • SAR444656 (KT-474)
  • Placebo
SanofiINTERVENTIONAL
CraniSeal Post Approval StudyNCT06406790RECRUITING
Leak, Cerebrospinal Fluid
  • CraniSeal
  • DuraSeal
Pramand LLCINTERVENTIONAL
Treatment of Supine Hypertension in Autonomic Failure (CPAP)NCT03312556RECRUITING
Supine Hypertension
Autonomic Failure
  • continuous positive airway pressure (CPAP)
  • Placebo
Vanderbilt University Medical CenterINTERVENTIONAL
A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Venous Leg UlcersNCT01138436COMPLETED
Ulcers
  • MEBO Wound Ointment (MEBO)
  • Standard of Care
Skingenix, Inc.INTERVENTIONAL
2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal CancersNCT03800693RECRUITING
Malignant Digestive System Neoplasm
  • Fluorouracil
  • Leucovorin
  • Oxaliplatin
Emory UniversityINTERVENTIONAL
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung CancerNCT05642195SUSPENDED
Non-Small Cell Lung Cancer
Non-Small Cell Lung Carcinoma
Carcinoma, Non-Small-Cell Lung
Carcinomas
  • Montanide (Registered Trademark) ISA-51 VG Adjuvant
  • H1299 Cell Lysates
  • N-803
  • Ventana PD-L1 (SP263 or SP142) assay
National Cancer Institute (NCI)INTERVENTIONAL
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac SurgeryNCT06271265RECRUITING
Postoperative Pain
  • EXPAREL
  • bupivacaine
Pacira Pharmaceuticals, IncINTERVENTIONAL
The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar FusionsNCT04140344RECRUITING
Lumbar Spine Degeneration
Lumbar Spine Instability
Lumbar Spondylosis
  • Text Message Group
Duke UniversityINTERVENTIONAL
Phase I Trial of High-Density Theta Burst Stimulation (hdTBS)NCT06868914RECRUITING
Healthy Volunteers
  • TMS (MagVenture MagPro 100 with MagOption)
National Institute on Drug Abuse (NIDA)INTERVENTIONAL
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage MesotheliomaNCT06654050NOT_YET_RECRUITING
Mesothelioma
Malignant Mesothelioma (MM)
Early-stage Mesothelioma
Subclinical Mesothelioma
BRCA1-Associated Protein-1 (BAP1) Mutations
Early-stage BAP1-associated Malignancies
  • alrizomadlin
National Cancer Institute (NCI)INTERVENTIONAL
Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative NeoplasmsNCT06303193NOT_YET_RECRUITING
Myelodysplastic Syndromes
  • pacritinib
National Cancer Institute (NCI)INTERVENTIONAL
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLCNCT06162221RECRUITING
Non-Small Cell Lung Cancer, NSCLC
KRAS, NRAS, HRAS-mutated NSCLC
KRAS G12C-mutated Solid Tumors, Lung Cancer
Lung Cancer Stage IV, Advanced Solid Tumor, Cancer
RAS G12D-mutated NSCLC
  • RMC-6291
  • RMC-6236
  • Pembrolizumab
  • Cisplatin
  • Carboplatin
  • Pemetrexed
  • RMC-9805
Revolution Medicines, Inc.INTERVENTIONAL
A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid TumorsNCT07182149RECRUITING
HNSCC
ESCC
Esophageal Adenocarcinoma
Gastric Adenocarcinoma
GEJ Adenocarcinoma
Ovarian Cancer
NSCLC
Cervical Cancer
Endometrial Cancer
Triple Negative Breast Cancer (TNBC)
  • NRM-823
Normunity AccelCo, Inc.INTERVENTIONAL
MMulti-Immune HR; Multi-Target Immunotherapy for High-Risk Multiple MyelomaNCT07029776NOT_YET_RECRUITING
Multiple Myeloma (MM)
  • teclistamab+daratumumab followed by talquetamab+daratumumab followed by duration treatment with daratumumab and lenalidomide extended/maintenance
  • melphalan (MEL)-based hematopietic stem cell transplantation (HSCT) followed by drug therapy
University of ArkansasINTERVENTIONAL
Post-Traumatic Stress Disorder Focused Psychodynamic PsychotherapyNCT03755401RECRUITING
PTSD
  • TFPP
  • TAU
Montefiore Medical CenterINTERVENTIONAL
The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant RecipientsNCT06639854RECRUITING
Cytomegalovirus Cell Mediated Immunity
Hematopoietic Cell Transplant
  • Hematopoietic Cell Transplant
  • Letermovir
M.D. Anderson Cancer CenterINTERVENTIONAL
Long-Term Neurologic and Neurocognitive Sequelae Following Pediatric Ebola Virus in LiberiaNCT06811129RECRUITING
Ebola
Post-Acute Ebola Syndrome
N/ANational Institute of Neurological Disorders and Stroke (NINDS)OBSERVATIONAL
Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological InvolvementNCT06923072RECRUITING
Kohlmeier-Degos Disease
Malignant Atrophic Papulosis
Degos Disease
Papulosis, Malignant Atrophic
  • Baricitinib
National Heart, Lung, and Blood Institute (NHLBI)INTERVENTIONAL
Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid TumorsNCT06504368RECRUITING
Solid Tumors, Adult
  • DCR-PDL1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk companyINTERVENTIONAL
Nivolumab With or Without Bevacizumab or Ipilimumab Before Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed by SurgeryNCT02210117ACTIVE_NOT_RECRUITING
Clear Cell Renal Cell Carcinoma
Metastatic Kidney Carcinoma
Stage IV Renal Cell Cancer AJCC v7
  • Bevacizumab
  • Biopsy
  • Ipilimumab
  • Laboratory Biomarker Analysis
  • Metastasectomy
  • Nivolumab
  • Therapeutic Conventional Surgery
M.D. Anderson Cancer CenterINTERVENTIONAL
My Best GI Eating StudyNCT05396846ACTIVE_NOT_RECRUITING
Colorectal Neoplasms
  • Eating Plan 1
  • Eating Plan 2
  • Eating Plan 3
University of MichiganINTERVENTIONAL
Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 GeneNCT06052631RECRUITING
PIEZO2-Deficiency Syndrome
N/ANational Center for Complementary and Integrative Health (NCCIH)OBSERVATIONAL
Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial FibrillationNCT04755283ACTIVE_NOT_RECRUITING
Atrial Fibrillation (AF)
Stroke
  • Abelacimab
  • Rivaroxaban
Anthos Therapeutics, Inc.INTERVENTIONAL
A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative ColitisNCT06867094RECRUITING
Colitis Ulcerative
  • SAR441566
  • SAR441566 matching Placebo
SanofiINTERVENTIONAL
Exploring the Effect of the Transcendental Meditation® Technique on Migraine Frequency and Functionality: A Single Arm StudyNCT06695156ACTIVE_NOT_RECRUITING
Migraine
Migraine With or Without Aura
  • Meditation
Maharishi International UniversityINTERVENTIONAL
RF Vapor Ablation Retreatment of Duodenal Mucosa in Non-responders With Type-2 Diabetes MellitusNCT06724822ACTIVE_NOT_RECRUITING
Diabetes Mellitus, Type 2
  • RF Vapor Ablation
Aqua Medical, Inc.INTERVENTIONAL
Shifting Options StudyNCT07225595RECRUITING
Prenatal Care
Prenatal Diagnosis
N/AThe Cleveland ClinicOBSERVATIONAL
Connors Protocol for the Management and Use of Stored Human Specimens (Stored Human Specimens)NCT03895645ENROLLING_BY_INVITATION
Healthy Volunteer Samples
N/ANational Institute of Allergy and Infectious Diseases (NIAID)OBSERVATIONAL
A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)NCT06980805RECRUITING
Subacute Cutaneous Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus
  • IMVT-1402
  • Placebo
Immunovant Sciences GmbHINTERVENTIONAL
The Acute Effects of Liquid IV's Pre-Workout Supplement on Muscle Endurance & Strength, Energy, and CognitionNCT07225608NOT_YET_RECRUITING
Physical Performance
Exercise Performance
Endurance Exercise
Perceived Exertion
Mood
Energy
  • proprietary pre-workout supplement
  • Control placebo
Applied Science & Performance InstituteINTERVENTIONAL
A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Diabetic Foot UlcersNCT01070433COMPLETED
Diabetic Foot Ulcers
  • MEBO Wound Ointment (MEBO)
  • Standard of Care
Skingenix, Inc.INTERVENTIONAL
Personalizing Financial IncentivesNCT07225426NOT_YET_RECRUITING
Obesity & Overweight
  • personalized financial incentives
University of UtahINTERVENTIONAL
P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant EnterobacteralesNCT05905055COMPLETED
Complicated Urinary Tract Infection
Acute Pyelonephritis
Hospital-acquired Bacterial Pneumonia
Ventilator-associated Bacterial Pneumonia
Complicated Intra-abdominal Infection
  • co-administration of cefepime and nacubactam
  • co-administration of aztreonam and nacubactam
  • BAT
Meiji Seika Pharma Co., Ltd.INTERVENTIONAL
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)NCT04929223RECRUITING
Metastatic Colorectal Cancer
  • Inavolisib
  • Bevacizumab
  • Cetuximab
  • Atezolizumab
  • Tiragolumab
  • SY-5609
  • Divarasib
  • FOLFOX
  • FOLFIRI
  • FoundationOne®Liquid CDx
Hoffmann-La RocheINTERVENTIONAL
Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)NCT07204977RECRUITING
Amyotrophic Lateral Sclerosis
Motor Neuron Disease
  • Acamprosate calcium
National Institute of Neurological Disorders and Stroke (NINDS)INTERVENTIONAL
Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord InjuryNCT04883463RECRUITING
Spinal Cord Injuries
  • Epidural stimulation
University of California, Los AngelesINTERVENTIONAL
Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell CarcinomaNCT06585410RECRUITING
Cutaneous Squamous Cell Carcinoma (CSCC)
  • Cemiplimab
  • Standard of care
Regeneron PharmaceuticalsINTERVENTIONAL
Treating Major Depression With Yoga Mono-therapyNCT06091527RECRUITING
Depression Mild
Depression Moderate
  • Yoga practice
  • Education
University of California, San FranciscoINTERVENTIONAL
Improving Women's Function After Pelvic RadiationNCT04544735ACTIVE_NOT_RECRUITING
Sexual Dysfunction
Pelvic Floor Disorders
Gynecologic Cancer
  • Integrated Physical Therapy and Coping Skills Training
Duke UniversityINTERVENTIONAL
Diet and Stress Management Combined With Advanced Therapy for Crohn's and Ulcerative ColitisNCT07168499RECRUITING
IBD (Inflammatory Bowel Disease)
  • Diet Management
  • Stress Management
Massachusetts General HospitalINTERVENTIONAL
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs TriamtereneNCT05125237COMPLETED
Hypertension
  • Amiloride
  • Triamterene
Brigham and Women's HospitalOBSERVATIONAL
Maintenance Zanzalintinib With Etoposide After HDCT in GCTNCT06937866RECRUITING
Germ Cell Tumor
  • Zanzalintinib
  • Etoposide Capsule
Indiana UniversityINTERVENTIONAL
A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)NCT06450639RECRUITING
Duchenne Muscular Dystrophy
  • Satralizumab
Hoffmann-La RocheINTERVENTIONAL
Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Support Therapy in Functional DyspepsiaNCT06360900RECRUITING
Functional Dyspepsia
  • Sensory device
  • Skills Building
  • Health Education
  • Subsensory device
Spaulding Rehabilitation HospitalINTERVENTIONAL
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)NCT05566795RECRUITING
Low-grade Glioma
Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma
Pediatric Low-grade Glioma
  • Tovorafenib
  • Chemotherapeutic Agent
Day One Biopharmaceuticals, Inc.INTERVENTIONAL
Real-World Outcomes of Nivolumab+Ipilimumab and Pembrolizumab+Lenvatinib Among US Advanced Renal Cell Carcinoma (aRCC) PatientsNCT06345183COMPLETED
Advanced Renal Cell Carcinoma (aRCC)
  • Nivolumab + Ipilimumab combination therapy
  • Pembrolizumab + Lenvatinib combination therapy
Bristol-Myers SquibbOBSERVATIONAL
Functional Outcomes of Cannabis Use (FOCUS) in Veterans With Posttraumatic Stress DisorderNCT04565028RECRUITING
PTSD
Cannabis-Related Disorder
  • Contingency Management (CM)
VA Office of Research and DevelopmentINTERVENTIONAL
C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)NCT03750981RECRUITING
Cancer Survivors
  • 12 week pilot intervention study.
Barbara Ann Karmanos Cancer InstituteINTERVENTIONAL
Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR)NCT07225530NOT_YET_RECRUITING
HIV Infections
HPV Infection
Cervical Cancer
  • iSTAR
Columbia UniversityINTERVENTIONAL
Developing Transcranial Neuromodulation Protocols for Learning and Decision-MakingNCT06561828RECRUITING
Normal Physiology
  • continuous Theta Burst Stimulation (cTBS)
  • intermittent Theta Burst Stimulation (iTBS)
  • sham Theta Burst Stimulation (sham TBS)
National Institute on Drug Abuse (NIDA)INTERVENTIONAL
Role of Stress CMR in Predicting Adverse Clinical Events in Patients With Known or Suspected IHDNCT01821924COMPLETED
Coronary Artery Disease
N/ABrigham and Women's HospitalOBSERVATIONAL
Randomized Stepped Wedge Study of Emapalumab in APECED EnteritisNCT07202598NOT_YET_RECRUITING
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Enteritis
  • Emapalumab
National Institute of Allergy and Infectious Diseases (NIAID)INTERVENTIONAL
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus LazertinibNCT06120140RECRUITING
Carcinoma, Non-Small-Cell Lung
  • Amivantamab IV
  • Amivantamab SC
  • Lazertinib
  • Doxycycline
  • Minocycline
  • Clindamycin
  • Chlorhexidine
  • Noncomedogenic skin moisturizer
  • Ruxolitinib
  • Tacrolimus
  • Zinc gluconate
  • Propranolol
  • Timolol
  • Clobetasol
Janssen Research & Development, LLCINTERVENTIONAL
A Tailored and Digital Approach to Address Equity and Support Well-being for Healthcare Workers in the Era of COVIDNCT05931432ACTIVE_NOT_RECRUITING
Depression, Anxiety
Satisfaction
Well-being
  • Comprehensive Well-Being Intervention
University of PennsylvaniaINTERVENTIONAL
Veliparib, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Non-Hodgkin LymphomaNCT00740805ACTIVE_NOT_RECRUITING
Ann Arbor Stage III Non-Hodgkin Lymphoma
Ann Arbor Stage IV Non-Hodgkin Lymphoma
Solid Neoplasm
  • Cyclophosphamide
  • Doxorubicin Hydrochloride
  • Laboratory Biomarker Analysis
  • Pharmacological Study
  • Veliparib
National Cancer Institute (NCI)INTERVENTIONAL
Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium TrialNCT02603341ACTIVE_NOT_RECRUITING
Breast Cancer
  • Photon
  • Proton
Abramson Cancer Center at Penn MedicineINTERVENTIONAL
Study of ARRY-614 Plus Either Nivolumab or Nivolumab+IpilimumabNCT04074967ACTIVE_NOT_RECRUITING
Renal Cell Carcinoma
Melanoma
Solid Tumor
Non-small Cell Lung Cancer
Head and Neck Squamous Cell Carcinoma
  • Phase Ib ARRY-614 + nivolumab
  • Phase Ib ARRY-614 + nivolumab+ipilimumab
  • Phase II ARRY-614 + nivolumab
  • Phase II ARRY-614 + nivolumab+ipilimumab (melanoma)
  • Phase II ARRY-614 + nivolumab+ipilimumab (RCC)
Dan ZandbergINTERVENTIONAL
Comparative Outcomes of Four Versus Two Balloon Inflation Points in Dacryoplasty for Primary Acquired Nasolacrimal Duct ObstructionNCT07225244RECRUITING
Primary Acquired Nasolacrimal Duct Obstruction
  • 2 point balloon dacryoplasty with LacriCATH®
  • 4 point balloon dacryoplasty with LacriCATH®
National Taiwan University HospitalINTERVENTIONAL
A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in GlioblastomaNCT04900792ACTIVE_NOT_RECRUITING
Glioblastoma
Glioblastoma Multiforme
  • Ferumoxytol injection
  • Pharmacological ascorbate
  • External beam radiation therapy
  • Temozolomide
Bryan AllenINTERVENTIONAL
Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or AstrocytomaNCT06860594RECRUITING
Astrocytoma, IDH-Mutant, Grade 2
Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant
Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant
Recurrent Astrocytoma, IDH-Mutant
Recurrent Astrocytoma, IDH-Mutant, Grade 3
Recurrent Astrocytoma, IDH-Mutant, Grade 4
Recurrent Glioblastoma, IDH-Wildtype
  • Biospecimen Collection
  • Computed Tomography
  • Intensity-Modulated Radiation Therapy
  • Magnetic Resonance Imaging
  • Triapine
National Cancer Institute (NCI)INTERVENTIONAL
GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder With Comorbid Anxiety and InsomniaNCT07115329NOT_YET_RECRUITING
Major Depressive Disorder
  • Zelquistinel
Syndeio Biosciences, IncINTERVENTIONAL
Cleveland African American Prostate Cancer ProjectNCT05469269RECRUITING
Prostate Cancer
  • Passive Education
  • Education by Community Navigator
  • Education at Community Outreach Screening Event
Case Comprehensive Cancer CenterINTERVENTIONAL
A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other TumorsNCT03972657RECRUITING
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Clear Cell Renal Cell Carcinoma (ccRCC)
  • REGN5678
  • Cemiplimab
Regeneron PharmaceuticalsINTERVENTIONAL
Targeted Motor Learning to Improve Gait for Individuals With Parkinson DiseaseNCT05864157RECRUITING
Parkinson Disease
  • Gait training without rhythmic auditory cues
  • TRAC
  • dTRAC
University of North Carolina, Chapel HillINTERVENTIONAL
PC001- A Study to Evaluate the Usability of PointCheckNCT04448301COMPLETED
Neoplasms
Neutropenia
  • PointCheck
Leuko Labs, Inc.INTERVENTIONAL
Tirzepatide in MetALDNCT07046819NOT_YET_RECRUITING
Metabolic Alcohol-associated Liver Disease
Alcohol Use Disorder
  • Tirzepatide
  • Placebo
National Institute on Alcohol Abuse and Alcoholism (NIAAA)INTERVENTIONAL
Phase I/II Study of the Anti-Programmed Death Ligand-1 Durvalumab Antibody (MEDI4736) in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Can...NCT02484404ACTIVE_NOT_RECRUITING
Colorectal Neoplasms
Breast Neoplasms
  • Olaparib
  • Cediranib
  • Durvalumab
National Cancer Institute (NCI)INTERVENTIONAL
A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following RadiotherapyNCT06413706RECRUITING
Glioma
  • Abemaciclib
  • Temozolomide
Eli Lilly and CompanyINTERVENTIONAL
Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationNCT07160179RECRUITING
Geographic Atrophy
Age-Related Macular Degeneration
  • ABBV-6628
  • SYFOVRE
AbbVieINTERVENTIONAL